SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1s7u H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-B ALPHA
CHAIN
(Mus
musculus) 		3 / 3 GLU A 128
GLU A 161
LEU A 103
 None
 0.60A 1v8bA-1s7uA:
undetectable		 1v8bA-1s7uA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1s7u H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-B ALPHA
CHAIN
(Mus
musculus) 		3 / 3 GLU A 128
GLU A 161
LEU A 103
 None
 0.62A 1v8bB-1s7uA:
undetectable		 1v8bB-1s7uA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1s7u H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-B ALPHA
CHAIN
(Mus
musculus) 		3 / 3 TRP A 167
GLU A  63
TYR A  59
 None
 0.87A 2a3aA-1s7uA:
undetectable		 2a3aA-1s7uA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 1s7u H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-B ALPHA
CHAIN
(Mus
musculus) 		4 / 5 ALA A 140
GLN A 141
ILE A 142
ARG A 145
 None
 1.44A 2z0aA-1s7uA:
undetectable		 2z0aA-1s7uA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1s7u H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-B ALPHA
CHAIN
(Mus
musculus) 		4 / 8 TYR A 123
TYR A  84
TYR A 118
HIS A  93
 None
 0.94A 2zm8A-1s7uA:
undetectable		 2zm8A-1s7uA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1s7u H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-B ALPHA
CHAIN
(Mus
musculus) 		4 / 8 TYR A 123
TYR A  84
TYR A 118
HIS A  93
 None
 0.98A 2zmaA-1s7uA:
undetectable		 2zmaA-1s7uA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1s7u H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, D-B ALPHA
CHAIN
(Mus
musculus) 		5 / 12 LEU A 114
PHE A  74
ALA A 117
ALA A 140
ILE A 142
 None
 0.97A 5veuB-1s7uA:
undetectable		 5veuB-1s7uA:
21.67