SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s8h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 8 LEU A   2
ALA A  18
ILE A  19
HIS A  48
 None
 0.39A 1sv9A-1s8hA:
21.0		 1sv9A-1s8hA:
64.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 6 LEU A   2
ALA A  18
HIS A  48
TYR A  52
 None
 1.27A 2dpzA-1s8hA:
21.0		 2dpzA-1s8hA:
64.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 5 LEU A   2
ILE A  19
GLY A  30
HIS A  48
 None
 0.74A 2otfA-1s8hA:
21.1		 2otfA-1s8hA:
64.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 5 LEU A   2
ALA A  18
ILE A  19
LYS A  69
 None
 0.30A 2othA-1s8hA:
21.0		 2othA-1s8hA:
64.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OUB_A_2TNA134_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 4 LEU A   2
ILE A  19
HIS A  48
LYS A  69
 None
 0.50A 2oubA-1s8hA:
20.8		 2oubA-1s8hA:
64.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 7 GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.48A 3bjwB-1s8hA:
20.6		 3bjwB-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		5 / 9 LYS A  16
TYR A 113
ASN A 114
LYS A 115
TYR A 117
 None
 0.76A 3bjwG-1s8hA:
20.3		 3bjwG-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		5 / 11 LEU A   5
GLY A   6
LYS A  16
SER A  21
LYS A 115
 None
 1.07A 3bjwE-1s8hA:
20.5		 3bjwE-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		5 / 9 LYS A  16
TYR A 113
ASN A 114
LYS A 115
TYR A 117
 None
 0.83A 3bjwA-1s8hA:
20.4		 3bjwA-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 6 GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.47A 3bjwE-1s8hA:
20.5		 3bjwE-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		5 / 12 LEU A   5
GLY A   6
LYS A  16
SER A  21
LYS A 115
 None
 0.90A 3bjwF-1s8hA:
20.4		 3bjwF-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 8 LYS A  16
TYR A 113
ASN A 114
LYS A 115
 None
 0.92A 3bjwD-1s8hA:
20.3		 3bjwD-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 7 GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.41A 3bjwF-1s8hA:
20.4		 3bjwF-1s8hA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 7 GLN A  11
GLY A  14
ARG A 107
LEU A 110
 None
 0.41A 3bjwH-1s8hA:
20.4		 3bjwH-1s8hA:
62.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 5 HIS A  33
GLY A  30
TYR A 120
TYR A  25
 None
 1.18A 4ae1B-1s8hA:
undetectable		 4ae1B-1s8hA:
12.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 4 LEU A   2
ALA A  18
ILE A  19
LYS A  69
 None
 0.32A 4eixA-1s8hA:
20.9		 4eixA-1s8hA:
64.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		3 / 3 TYR A  52
LYS A  53
LYS A  49
 None
SO4  A 134 (-3.3A)
SO4  A 134 (-2.5A)
 1.17A 5dbyA-1s8hA:
undetectable		 5dbyA-1s8hA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		3 / 3 TYR A 113
LYS A 118
LYS A 115
 None
 1.14A 5dbyA-1s8hA:
undetectable		 5dbyA-1s8hA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 4 HIS A  68
LEU A 106
TYR A  22
GLY A   6
 None
 1.18A 6n91A-1s8hA:
undetectable		 6n91A-1s8hA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1s8h PHOSPHOLIPASE A2
HOMOLOG
(Agkistrodon
contortrix) 		4 / 4 HIS A  68
LEU A 106
TYR A  22
GLY A   6
 None
 1.18A 6n91B-1s8hA:
undetectable		 6n91B-1s8hA:
20.51