SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 5 LEU A  96
LEU A  94
LEU A 217
GLY A  61
 None
 0.83A 1a4lC-1s9cA:
undetectable		 1a4lC-1s9cA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		3 / 3 GLN A  92
TYR A 188
ARG A 189
 None
 0.95A 1gtbA-1s9cA:
undetectable		 1gtbA-1s9cA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		3 / 3 ASP A  53
PHE A  46
SER A 237
 None
 0.72A 3i5uB-1s9cA:
undetectable		 3i5uB-1s9cA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		3 / 3 ASP A  43
ARG A 225
ASP A  53
 None
 0.80A 4fp9A-1s9cA:
undetectable		 4fp9A-1s9cA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		3 / 3 ASP A  43
ARG A 225
ASP A  53
 None
 0.88A 4fp9C-1s9cA:
undetectable		 4fp9C-1s9cA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 6 TYR A  30
PRO A  58
PHE A 220
PHE A 239
 None
 1.05A 4kf9A-1s9cA:
0.0		 4kf9A-1s9cA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		3 / 3 ASN A 234
ASP A  43
ASP A 178
 None
 0.68A 4obwD-1s9cA:
undetectable		 4obwD-1s9cA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 4 SER A 223
ALA A 224
GLN A  92
THR A  59
 None
 1.28A 5n0rA-1s9cA:
undetectable		 5n0rA-1s9cA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 4 SER A 223
ALA A 224
GLN A  92
THR A  59
 None
 1.27A 5n0sA-1s9cA:
0.2		 5n0sA-1s9cA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 5 SER A 223
ALA A 224
GLN A  92
THR A  59
 None
 1.27A 5n0tA-1s9cA:
undetectable		 5n0tA-1s9cA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 4 SER A 223
ALA A 224
GLN A  92
THR A  59
 None
 1.25A 5n0wA-1s9cA:
undetectable		 5n0wA-1s9cA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 5 SER A 223
ALA A 224
GLN A  92
THR A  59
 None
 1.25A 5n0wB-1s9cA:
undetectable		 5n0wB-1s9cA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 4 SER A 223
ALA A 224
GLN A  92
THR A  59
 None
 1.28A 5n0xA-1s9cA:
undetectable		 5n0xA-1s9cA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 5 SER A 223
ALA A 224
GLN A  92
THR A  59
 None
 1.28A 5n4iA-1s9cA:
undetectable		 5n4iA-1s9cA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 1s9c PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2
(Homo
sapiens) 		4 / 6 TYR A  93
PRO A  58
LEU A  57
LEU A  96
 None
 1.18A 5tl8A-1s9cA:
undetectable		 5tl8A-1s9cA:
20.73