SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1s9k NUCLEAR FACTOR OF
ACTIVATED T-CELLS,
CYTOPLASMIC 2
(Homo
sapiens) 		4 / 4 ILE C 567
LEU C 468
VAL C 545
ILE C 460
 None
 0.91A 1fm6D-1s9kC:
undetectable		 1fm6D-1s9kC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1s9k NUCLEAR FACTOR OF
ACTIVATED T-CELLS,
CYTOPLASMIC 2
PROTO-ONCOGENE
PROTEIN C-FOS
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP D 170
ASP D 163
ASP C 464
 None
 0.76A 2igtA-1s9kD:
undetectable		 2igtA-1s9kD:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1s9k NUCLEAR FACTOR OF
ACTIVATED T-CELLS,
CYTOPLASMIC 2
PROTO-ONCOGENE
PROTEIN C-FOS
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP D 170
ASP D 163
ASP C 464
 None
 0.78A 2igtB-1s9kD:
undetectable		 2igtB-1s9kD:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1s9k NUCLEAR FACTOR OF
ACTIVATED T-CELLS,
CYTOPLASMIC 2
(Homo
sapiens) 		4 / 5 GLU C 641
PRO C 643
ILE C 642
GLY C 593
 None
 1.13A 2qeuA-1s9kC:
undetectable
2qeuC-1s9kC:
undetectable		 2qeuA-1s9kC:
22.94
2qeuC-1s9kC:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 1s9k NUCLEAR FACTOR OF
ACTIVATED T-CELLS,
CYTOPLASMIC 2
(Homo
sapiens) 		4 / 6 ARG C 541
TYR C 474
THR C 462
ALA C 463
 None
 1.43A 2ql8A-1s9kC:
0.0
2ql8B-1s9kC:
0.0		 2ql8A-1s9kC:
19.64
2ql8B-1s9kC:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 1s9k NUCLEAR FACTOR OF
ACTIVATED T-CELLS,
CYTOPLASMIC 2
(Homo
sapiens) 		4 / 8 GLN C 669
PRO C 670
TYR C 659
GLN C 583
 None
 1.03A 3oyaA-1s9kC:
undetectable		 3oyaA-1s9kC:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 1s9k NUCLEAR FACTOR OF
ACTIVATED T-CELLS,
CYTOPLASMIC 2
(Homo
sapiens) 		5 / 9 GLU C 413
ILE C 412
HIS C 440
PHE C 546
THR C 487
 None
 1.33A 4pxxA-1s9kC:
undetectable		 4pxxA-1s9kC:
21.77