SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1s9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		3 / 3 VAL A  34
ALA A  31
HIS A  28
 None
 0.76A 1q23C-1s9uA:
undetectable		 1q23C-1s9uA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		3 / 3 VAL A  34
ALA A  31
HIS A  28
 None
 0.70A 1q23H-1s9uA:
undetectable		 1q23H-1s9uA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		4 / 5 LEU A 131
ALA A 135
TRP A 189
LEU A 151
 None
 0.97A 2oaxA-1s9uA:
undetectable		 2oaxA-1s9uA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		5 / 9 TRP A  46
THR A 185
LEU A  20
LEU A  17
GLY A  18
 None
 1.47A 4c9kA-1s9uA:
0.0		 4c9kA-1s9uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		5 / 9 TRP A  46
THR A 185
LEU A  20
LEU A  17
GLY A  18
 None
 1.45A 4c9kB-1s9uA:
0.0		 4c9kB-1s9uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		5 / 8 TRP A  46
THR A 185
LEU A  20
LEU A  17
GLY A  18
 None
 1.48A 4c9nA-1s9uA:
undetectable		 4c9nA-1s9uA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		4 / 6 VAL A  90
TRP A  87
TRP A 158
PHE A 162
 None
 1.40A 4d33A-1s9uA:
0.0
4d33B-1s9uA:
0.0		 4d33A-1s9uA:
21.28
4d33B-1s9uA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		5 / 12 TRP A  42
TRP A  46
LEU A  53
LEU A 178
PHE A 174
 None
 1.21A 4foxG-1s9uA:
undetectable		 4foxG-1s9uA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		5 / 8 VAL A  56
LEU A 181
LEU A 184
ASP A 164
ILE A 167
 None
 1.39A 4lzrA-1s9uA:
2.4		 4lzrA-1s9uA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		3 / 3 LEU A 131
LEU A 134
TRP A 137
 None
PEG  A 305 (-4.6A)
None
 0.88A 5nwuA-1s9uA:
0.0		 5nwuA-1s9uA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		4 / 4 ALA A  11
ALA A  14
ALA A 136
ALA A 139
 None
None
None
PEG  A 304 ( 4.3A)
 0.77A 6gtqA-1s9uA:
undetectable
6gtqB-1s9uA:
undetectable		 6gtqA-1s9uA:
20.35
6gtqB-1s9uA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES
(Salmonella
enterica) 		4 / 4 ALA A 136
ALA A 139
ALA A  11
ALA A  14
 None
PEG  A 304 ( 4.3A)
None
None
 0.77A 6gtqA-1s9uA:
undetectable
6gtqB-1s9uA:
undetectable		 6gtqA-1s9uA:
20.35
6gtqB-1s9uA:
20.35