SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		5 / 11 SER A 148
LEU A 108
GLY A 140
HIS A 221
GLU A 219
 MN  A 600 ( 4.2A)
None
None
None
None
 1.39A 1iolA-1sbdA:
undetectable		 1iolA-1sbdA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		4 / 7 LYS A  31
LEU A  32
GLN A  33
PHE A  74
 None
 1.01A 1v55P-1sbdA:
undetectable
1v55W-1sbdA:
undetectable		 1v55P-1sbdA:
21.99
1v55W-1sbdA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		5 / 12 GLY A  89
ALA A  87
PHE A 128
THR A 127
LEU A 156
 None
GAL  A 847 ( 4.4A)
GAL  A 847 (-4.0A)
None
None
 0.98A 3dh0A-1sbdA:
undetectable		 3dh0A-1sbdA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		4 / 5 ASP A 133
ASP A 192
ASN A 142
GLU A 124
 MN  A 600 ( 2.8A)
None
None
MN  A 600 (-2.6A)
 1.37A 3vywD-1sbdA:
undetectable		 3vywD-1sbdA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		3 / 3 ASN A 130
ASP A  88
ASP A 215
 CA  A 601 ( 2.9A)
GAL  A 847 (-2.8A)
GAL  A 847 ( 2.9A)
 0.82A 4obwD-1sbdA:
undetectable		 4obwD-1sbdA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		4 / 8 ASN A  17
VAL A  26
LEU A  32
GLY A 207
 None
 0.87A 4r3aA-1sbdA:
undetectable		 4r3aA-1sbdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		5 / 8 ALA A  72
ALA A  71
ILE A 166
ALA A 170
LEU A 175
 None
 1.38A 4v1fA-1sbdA:
undetectable
4v1fB-1sbdA:
undetectable		 4v1fA-1sbdA:
14.62
4v1fB-1sbdA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		5 / 12 LEU A  94
LEU A 200
ILE A  59
LYS A   1
VAL A 194
 None
 0.98A 4y0sA-1sbdA:
undetectable		 4y0sA-1sbdA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 1sbd SOYBEAN AGGLUTININ
(Glycine
max) 		5 / 12 ILE A  25
LEU A  94
GLY A  22
LEU A  34
PHE A  74
 None
 0.99A 6a7pA-1sbdA:
undetectable		 6a7pA-1sbdA:
17.38