SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sbp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
4 / 8 ILE A 254
VAL A  36
GLY A 251
LEU A 246
None
0.90A 1dzmA-1sbpA:
undetectable
1dzmA-1sbpA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
4 / 6 GLY A  43
ASP A  11
GLY A 175
SER A 129
None
0.92A 1eswA-1sbpA:
undetectable
1eswA-1sbpA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
3 / 3 GLN A 152
TYR A 137
ARG A 134
None
0.95A 1gtbA-1sbpA:
undetectable
1gtbA-1sbpA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
3 / 3 PHE A  99
TYR A 143
PRO A 213
None
1.13A 1mcnA-1sbpA:
undetectable
1mcnB-1sbpA:
undetectable
1mcnP-1sbpA:
undetectable
1mcnA-1sbpA:
23.32
1mcnB-1sbpA:
23.32
1mcnP-1sbpA:
2.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 ALA A 133
GLY A 132
GLY A 131
GLN A 294
ASP A  68
None
SO4  A 311 (-3.1A)
SO4  A 311 (-3.4A)
None
None
1.17A 2c49A-1sbpA:
undetectable
2c49A-1sbpA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
4 / 7 ARG A 261
LEU A 280
PHE A 281
LEU A 278
None
1.00A 2dysC-1sbpA:
undetectable
2dysJ-1sbpA:
undetectable
2dysC-1sbpA:
22.60
2dysJ-1sbpA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 LYS A 270
GLY A 251
ALA A  23
ALA A 256
ASN A 258
None
1.01A 3jb3A-1sbpA:
0.0
3jb3A-1sbpA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 PHE A 298
ILE A 217
ALA A 219
ALA A 173
GLY A  46
None
None
None
SO4  A 311 (-3.4A)
None
1.02A 3nxuA-1sbpA:
undetectable
3nxuA-1sbpA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 ALA A 173
GLY A 132
GLY A  44
SER A  45
ALA A 191
SO4  A 311 (-3.4A)
SO4  A 311 (-3.1A)
SO4  A 311 (-3.5A)
SO4  A 311 (-4.4A)
None
0.92A 3ou6A-1sbpA:
undetectable
3ou6A-1sbpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 TYR A  10
ALA A 173
GLY A 132
GLY A  44
ALA A 191
SO4  A 311 (-4.8A)
SO4  A 311 (-3.4A)
SO4  A 311 (-3.1A)
SO4  A 311 (-3.5A)
None
1.10A 3ou6A-1sbpA:
undetectable
3ou6A-1sbpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 ALA A 173
GLY A 132
GLY A  44
SER A  45
ALA A 191
SO4  A 311 (-3.4A)
SO4  A 311 (-3.1A)
SO4  A 311 (-3.5A)
SO4  A 311 (-4.4A)
None
0.91A 3ou6B-1sbpA:
undetectable
3ou6B-1sbpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 TYR A  10
ALA A 173
GLY A 132
GLY A  44
ALA A 191
SO4  A 311 (-4.8A)
SO4  A 311 (-3.4A)
SO4  A 311 (-3.1A)
SO4  A 311 (-3.5A)
None
1.10A 3ou6B-1sbpA:
undetectable
3ou6B-1sbpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 ALA A 173
GLY A 132
GLY A  44
SER A  45
ALA A 191
SO4  A 311 (-3.4A)
SO4  A 311 (-3.1A)
SO4  A 311 (-3.5A)
SO4  A 311 (-4.4A)
None
0.92A 3ou7B-1sbpA:
undetectable
3ou7B-1sbpA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
3 / 3 THR A  96
SER A  95
ARG A 261
None
0.82A 3phnA-1sbpA:
undetectable
3phnA-1sbpA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
3 / 3 PRO A 213
ASP A 111
GLU A 215
None
0.80A 3v4tC-1sbpA:
0.0
3v4tC-1sbpA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 PHE A 275
PRO A 276
PRO A 213
VAL A 188
ALA A 196
None
1.26A 4a84A-1sbpA:
0.0
4a84A-1sbpA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 8 LEU A 243
LEU A 246
TYR A  20
ASN A  21
ILE A  38
None
1.44A 4lzrA-1sbpA:
undetectable
4lzrA-1sbpA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
4 / 8 THR A  62
GLY A  43
GLY A  44
ASP A  68
None
None
SO4  A 311 (-3.5A)
None
0.83A 4qvvK-1sbpA:
undetectable
4qvvL-1sbpA:
undetectable
4qvvK-1sbpA:
21.41
4qvvL-1sbpA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
4 / 8 THR A  62
GLY A  43
GLY A  44
ASP A  68
None
None
SO4  A 311 (-3.5A)
None
0.82A 4qvvY-1sbpA:
undetectable
4qvvZ-1sbpA:
undetectable
4qvvY-1sbpA:
21.41
4qvvZ-1sbpA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
4 / 5 ARG A 261
LEU A 280
PHE A 281
LEU A 278
None
1.02A 5iy5P-1sbpA:
undetectable
5iy5W-1sbpA:
undetectable
5iy5P-1sbpA:
22.43
5iy5W-1sbpA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
5 / 12 TYR A 242
LEU A 243
VAL A 229
VAL A  52
LEU A  16
None
1.20A 6djzA-1sbpA:
undetectable
6djzA-1sbpA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
1sbp SULFATE-BINDING
PROTEIN

(Salmonella
enterica)
3 / 3 GLN A  40
TYR A  17
ASN A  21
None
0.99A 6dwdC-1sbpA:
undetectable
6dwdC-1sbpA:
20.65