SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sbs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 1sbs MONOCLONAL ANTIBODY
3A2
(Mus
musculus) 		5 / 12 VAL H   2
MET H  34
ARG H  74
VAL H  81
TYR H 112
 None
 0.87A 3qxvB-1sbsH:
19.8		 3qxvB-1sbsH:
52.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1sbs MONOCLONAL ANTIBODY
3A2
(Mus
musculus) 		5 / 5 SER H 122
ALA H 124
PHE H 156
LEU H 180
ASP H 183
 None
 0.69A 5mthA-1sbsH:
26.8		 5mthA-1sbsH:
69.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 1sbs MONOCLONAL ANTIBODY
3A2
(Mus
musculus) 		3 / 3 TRP H  33
ILE H  51
ASP H  50
 None
 0.85A 6i0y7-1sbsH:
undetectable		 6i0y7-1sbsH:
10.64