SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1sc3 INTERLEUKIN-1 BETA
CONVERTASE
(Homo
sapiens) 		5 / 12 ASN A 170
PHE A 173
ILE A 261
GLY A 242
ILE A 243
 None
 1.31A 4djfA-1sc3A:
undetectable		 4djfA-1sc3A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1sc3 INTERLEUKIN-1 BETA
CONVERTASE
(Homo
sapiens) 		4 / 7 ILE A 282
MET A 211
THR A 212
LEU A 215
 None
 0.94A 5xdqN-1sc3A:
undetectable
5xdqW-1sc3A:
undetectable		 5xdqN-1sc3A:
15.28
5xdqW-1sc3A:
19.85