SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 GLN A 246
ILE A 217
HIS A 183
 None
 0.68A 1fm9A-1sddA:
undetectable		 1fm9A-1sddA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 TRP B1841
VAL B1862
TRP B1840
 None
 1.35A 1gmkC-1sddB:
undetectable
1gmkD-1sddB:
undetectable		 1gmkC-1sddB:
2.65
1gmkD-1sddB:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 GLN A 246
ILE A 217
HIS A 183
 None
 0.68A 1k74A-1sddA:
undetectable		 1k74A-1sddA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 5 GLU B1951
GLY B1978
THR B1949
PHE B1952
 None
 1.25A 1kqbA-1sddB:
undetectable
1kqbB-1sddB:
undetectable		 1kqbA-1sddB:
15.87
1kqbB-1sddB:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_A_CLWA906_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 5 PRO B1994
VAL B1996
TYR B1780
MET B1779
 None
 1.49A 1m8dA-1sddB:
0.0		 1m8dA-1sddB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8D_B_CLWB907_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 5 PRO B1994
VAL B1996
TYR B1780
MET B1779
 None
 1.50A 1m8dB-1sddB:
0.0		 1m8dB-1sddB:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 1sdd COAGULATION FACTOR V
COAGULATION FACTOR V
(Bos
taurus;
Bos
taurus) 		5 / 11 GLU B1846
HIS A  85
HIS B1804
LEU B1842
PRO B1858
 CU  B2190 ( 4.9A)
None
CU  B2190 (-3.7A)
None
None
 1.08A 1mjqA-1sddB:
undetectable
1mjqB-1sddB:
undetectable		 1mjqA-1sddB:
10.24
1mjqB-1sddB:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 4 HIS A  85
GLU A  96
HIS B1804
HIS B1802
 None
None
CU  B2190 (-3.7A)
CU  B2190 (-3.3A)
 1.28A 1uttA-1sddA:
undetectable		 1uttA-1sddA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 8 LEU B1932
ILE B1935
ILE B2000
ILE B2002
 None
 0.81A 2bu8A-1sddB:
undetectable		 2bu8A-1sddB:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 7 LEU B1843
PHE B1859
MET B1833
LEU B1808
 None
 0.94A 2eikA-1sddB:
undetectable
2eikJ-1sddB:
undetectable		 2eikA-1sddB:
20.53
2eikJ-1sddB:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 8 LEU B1843
PHE B1859
MET B1833
LEU B1808
 None
 0.93A 2eilN-1sddB:
undetectable
2eilW-1sddB:
0.0		 2eilN-1sddB:
20.53
2eilW-1sddB:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 7 TYR A  91
GLY A  97
TYR A 145
ASP A 112
 None
None
None
CA  A2184 (-2.5A)
 0.97A 2g70A-1sddA:
undetectable		 2g70A-1sddA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 7 TYR A  91
GLY A  97
TYR A 145
ASP A 112
 None
None
None
CA  A2184 (-2.5A)
 1.02A 2g70B-1sddA:
undetectable		 2g70B-1sddA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 6 TYR A  91
GLY A  97
TYR A 145
ASP A 112
 None
None
None
CA  A2184 (-2.5A)
 0.99A 2g72A-1sddA:
undetectable		 2g72A-1sddA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 7 TYR A  91
GLY A  97
TYR A 145
ASP A 112
 None
None
None
CA  A2184 (-2.5A)
 1.00A 2g72B-1sddA:
undetectable		 2g72B-1sddA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 6 GLY B2139
PRO B2164
LYS B2165
THR B2166
 None
 0.70A 2m2oB-1sddB:
undetectable		 2m2oB-1sddB:
3.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 4 HIS A  85
GLU A  96
HIS B1804
HIS B1802
 None
None
CU  B2190 (-3.7A)
CU  B2190 (-3.3A)
 1.33A 2ozrE-1sddA:
undetectable		 2ozrE-1sddA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 GLY A  97
ASP A 112
SER A  83
 None
CA  A2184 (-2.5A)
None
 0.72A 2qhfA-1sddA:
undetectable		 2qhfA-1sddA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 11 ILE B2000
LEU B2013
ASN B1980
ILE B1922
LEU B1872
 None
 1.26A 3a50C-1sddB:
undetectable		 3a50C-1sddB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 5 ILE B1798
HIS B1799
ARG B1796
GLY B1793
 None
 1.19A 3b9mA-1sddB:
undetectable		 3b9mA-1sddB:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 8 ALA A  86
VAL A  72
GLY A 160
ILE A 159
ILE A  84
 None
 1.22A 3ekpA-1sddA:
undetectable		 3ekpA-1sddA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		6 / 12 GLY B1871
GLY B1934
GLY B2019
THR B1933
PHE B1977
ILE B1935
 None
 1.40A 3elwA-1sddB:
undetectable		 3elwA-1sddB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 TYR A  91
GLY A  97
ASP A 112
 None
None
CA  A2184 (-2.5A)
 0.70A 3ou6C-1sddA:
undetectable		 3ou6C-1sddA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1sdd COAGULATION FACTOR V
COAGULATION FACTOR V
(Bos
taurus;
Bos
taurus) 		4 / 5 LEU B1818
GLN A  87
HIS A 142
GLY B1819
 None
 1.18A 3pp1A-1sddB:
undetectable		 3pp1A-1sddB:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 ASN A  76
ALA A  10
LYS A  77
 None
 0.97A 3runA-1sddA:
undetectable		 3runA-1sddA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 6 THR A  61
GLY A 160
ILE A 230
LEU A 162
 None
 1.25A 4ac9C-1sddA:
undetectable		 4ac9C-1sddA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 6 THR A  61
GLY A 160
ILE A 230
LEU A 162
 None
 1.23A 4acaC-1sddA:
undetectable		 4acaC-1sddA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 12 ALA A  10
ILE A 230
TYR A 144
LEU A  62
LEU A 162
 None
 1.18A 4l9qB-1sddA:
undetectable		 4l9qB-1sddA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 12 ASP A 112
HIS A  85
GLY A  97
HIS B1804
GLY B1805
 CA  A2184 (-2.5A)
None
None
CU  B2190 (-3.7A)
None
 1.21A 4lxzA-1sddA:
undetectable		 4lxzA-1sddA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 12 ASP A 112
HIS A  85
GLY A  97
HIS B1804
GLY B1805
 CA  A2184 (-2.5A)
None
None
CU  B2190 (-3.7A)
None
 1.22A 4lxzC-1sddA:
undetectable		 4lxzC-1sddA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 THR B2005
THR B1914
PHE B1916
 None
 0.62A 5cxvA-1sddB:
undetectable		 5cxvA-1sddB:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 LEU A 158
PHE A 190
ILE A 159
 None
 0.73A 5dzk1-1sddA:
undetectable
5dzkF-1sddA:
undetectable
5dzkM-1sddA:
undetectable		 5dzk1-1sddA:
3.45
5dzkF-1sddA:
20.32
5dzkM-1sddA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 6 LEU B1707
LEU B1792
LEU B1790
HIS B1630
 None
 0.97A 5gs4A-1sddB:
undetectable		 5gs4A-1sddB:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 12 LEU B2015
GLY B1939
THR B1985
LEU B1872
ASN B1899
 None
 0.99A 5nfjA-1sddB:
undetectable		 5nfjA-1sddB:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 12 LEU B2015
GLY B1939
THR B1985
LEU B1872
ASN B1899
 None
 1.00A 5nfjB-1sddB:
undetectable		 5nfjB-1sddB:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 12 LEU B2015
GLY B1939
THR B1985
LEU B1872
ASN B1899
 None
 0.99A 5nfjC-1sddB:
undetectable		 5nfjC-1sddB:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		5 / 8 VAL B2109
ILE B2162
LEU B2173
ILE B2095
ASN B2149
 None
 1.30A 5numA-1sddB:
undetectable		 5numA-1sddB:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 ARG B1778
PRO B1775
TYR B1956
 None
 0.78A 5tzoB-1sddB:
undetectable		 5tzoB-1sddB:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 5 MET B1733
TYR B1689
GLY B1705
GLY B1604
 None
 1.14A 5x7pA-1sddB:
4.8		 5x7pA-1sddB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		4 / 5 TYR B1689
TYR B1690
GLY B1705
GLY B1604
 None
 1.11A 5x7pA-1sddB:
4.8		 5x7pA-1sddB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1sdd COAGULATION FACTOR V
(Bos
taurus) 		3 / 3 GLN A 246
ILE A 217
HIS A 183
 None
 0.67A 5z12B-1sddA:
undetectable		 5z12B-1sddA:
14.63