SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sdo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 1sdo BSTYI
(Geobacillus
stearothermophil
us) 		5 / 10 VAL A 156
VAL A  18
ILE A 199
PRO A 195
GLY A  12
 None
 1.00A 13gsA-1sdoA:
undetectable		 13gsA-1sdoA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)		 1sdo BSTYI
(Geobacillus
stearothermophil
us) 		5 / 9 VAL A 156
VAL A  18
ILE A 199
PRO A 195
GLY A  12
 None
 1.01A 13gsB-1sdoA:
undetectable		 13gsB-1sdoA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 1sdo BSTYI
(Geobacillus
stearothermophil
us) 		4 / 8 LEU A  68
ILE A 160
ILE A  30
ILE A  31
 None
 0.80A 2bu8A-1sdoA:
undetectable		 2bu8A-1sdoA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1sdo BSTYI
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 157
TYR A 177
LEU A 161
VAL A 137
LEU A  13
 None
 1.24A 3g9eA-1sdoA:
0.0		 3g9eA-1sdoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 1sdo BSTYI
(Geobacillus
stearothermophil
us) 		4 / 5 GLN A 100
ILE A 104
TYR A  81
GLU A 110
 None
 1.22A 4a99D-1sdoA:
undetectable		 4a99D-1sdoA:
24.39