SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1se8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		5 / 12 ALA A  28
GLY A  26
GLU A  31
ALA A  63
LEU A  20
 None
 0.94A 1mjqC-1se8A:
undetectable
1mjqD-1se8A:
undetectable		 1mjqC-1se8A:
19.83
1mjqD-1se8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		5 / 10 GLU A  31
ALA A  63
LEU A  20
ALA A  28
GLY A  26
 None
 0.95A 1mjqG-1se8A:
undetectable
1mjqH-1se8A:
undetectable		 1mjqG-1se8A:
19.83
1mjqH-1se8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		5 / 12 ALA A  28
GLY A  26
GLU A  31
ALA A  63
LEU A  20
 None
 0.96A 1mjqI-1se8A:
undetectable
1mjqJ-1se8A:
undetectable		 1mjqI-1se8A:
19.83
1mjqJ-1se8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		5 / 10 THR A 139
VAL A 160
VAL A 175
VAL A  99
ASP A 179
 None
 1.39A 2qboA-1se8A:
undetectable		 2qboA-1se8A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		5 / 12 GLY A  12
SER A 126
ALA A  15
VAL A 123
VAL A  77
 None
 0.94A 2yvlA-1se8A:
undetectable		 2yvlA-1se8A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		5 / 9 VAL A 223
ILE A 144
VAL A 153
ALA A 152
ALA A 225
 None
 1.15A 4oqrA-1se8A:
undetectable		 4oqrA-1se8A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		4 / 5 ASP A  17
VAL A 123
ASP A 118
GLY A 121
 None
 1.21A 4xp6A-1se8A:
undetectable		 4xp6A-1se8A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		3 / 3 VAL A 223
HIS A 176
VAL A 160
 None
 0.70A 5jmnC-1se8A:
0.0		 5jmnC-1se8A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1se8 SINGLE-STRAND
BINDING PROTEIN
(Deinococcus
radiodurans) 		3 / 3 VAL A 228
GLU A 229
ILE A 201
 None
 0.63A 6f7lB-1se8A:
undetectable		 6f7lB-1se8A:
21.21