SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1seh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 1seh DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Escherichia
coli) 		5 / 12 LEU A  97
ILE A  89
ILE A  59
PHE A 122
LEU A  55
 UMP  A 777 (-4.7A)
UMP  A 777 (-3.9A)
None
None
None
 1.22A 1xdkB-1sehA:
undetectable		 1xdkB-1sehA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 1seh DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Escherichia
coli) 		3 / 3 ARG A  13
PHE A  18
PRO A  19
 None
 0.65A 3zoaB-1sehA:
undetectable		 3zoaB-1sehA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1seh DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Escherichia
coli) 		4 / 7 LEU A  33
THR A  53
PRO A  21
LEU A  10
 None
 1.02A 5fxtA-1sehA:
undetectable		 5fxtA-1sehA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 1seh DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Escherichia
coli) 		3 / 3 ILE A  99
ILE A  80
MET A  68
 None
None
UMP  A 777 (-4.4A)
 0.65A 5i9yA-1sehA:
undetectable		 5i9yA-1sehA:
16.77