SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 1sei RIBOSOMAL PROTEIN S8
(Geobacillus
stearothermophil
us) 		5 / 9 ILE A  31
VAL A   1
ILE A 125
ILE A  38
ILE A  35
 None
 0.90A 1hshB-1seiA:
undetectable		 1hshB-1seiA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 1sei RIBOSOMAL PROTEIN S8
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  10
ILE A 103
ILE A  38
ALA A  36
 None
 0.84A 2i30A-1seiA:
undetectable		 2i30A-1seiA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 1sei RIBOSOMAL PROTEIN S8
(Geobacillus
stearothermophil
us) 		4 / 7 ILE A  13
ARG A  14
GLY A  74
VAL A 129
 None
 0.83A 4a3uB-1seiA:
undetectable		 4a3uB-1seiA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1sei RIBOSOMAL PROTEIN S8
(Geobacillus
stearothermophil
us) 		4 / 8 GLY A  98
ASN A  97
PHE A  44
ILE A 101
 None
 0.86A 4j4vC-1seiA:
undetectable		 4j4vC-1seiA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1sei RIBOSOMAL PROTEIN S8
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A   1
GLU A 124
SER A 105
THR A  11
ARG A  84
 None
 1.46A 5m54B-1seiA:
undetectable		 5m54B-1seiA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 1sei RIBOSOMAL PROTEIN S8
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A  75
ILE A  35
ALA A  16
LEU A  59
LEU A  63
 None
 1.10A 6ie8A-1seiA:
undetectable		 6ie8A-1seiA:
21.72