SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1seq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1seq MONOCLONAL ANTIBODY
MNAC13
(Mus
musculus) 		4 / 5 PRO H 184
VAL H 187
THR H 153
GLY H 157
 None
 1.11A 3elzB-1seqH:
undetectable		 3elzB-1seqH:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1seq MONOCLONAL ANTIBODY
MNAC13
(Mus
musculus) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.82A 5ecoD-1seqH:
undetectable		 5ecoD-1seqH:
17.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1seq MONOCLONAL ANTIBODY
MNAC13
(Mus
musculus) 		5 / 5 SER H 112
ALA H 114
PHE H 146
LEU H 170
ASP H 173
 None
 0.65A 5mthA-1seqH:
27.4		 5mthA-1seqH:
70.98