SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sfr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.73A 1av2C-1sfrA:
undetectable
1av2D-1sfrA:
undetectable		 1av2C-1sfrA:
6.90
1av2D-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.96A 1grmA-1sfrA:
undetectable		 1grmA-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.96A 1grmB-1sfrA:
undetectable		 1grmB-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.92A 1jnoA-1sfrA:
undetectable		 1jnoA-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.92A 1jnoB-1sfrA:
undetectable		 1jnoB-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.91A 1jo3A-1sfrA:
undetectable		 1jo3A-1sfrA:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.91A 1jo3B-1sfrA:
undetectable		 1jo3B-1sfrA:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.87A 1jo4A-1sfrA:
undetectable		 1jo4A-1sfrA:
5.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.87A 1jo4B-1sfrA:
undetectable		 1jo4B-1sfrA:
5.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 133
SER A 131
LEU A  39
HIS A 139
GLU A  98
 None
 1.25A 1kw0A-1sfrA:
undetectable		 1kw0A-1sfrA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.90A 1magA-1sfrA:
undetectable		 1magA-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.90A 1magB-1sfrA:
undetectable		 1magB-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 133
SER A 131
LEU A  39
HIS A 139
GLU A  98
 None
 1.21A 1mmkA-1sfrA:
undetectable		 1mmkA-1sfrA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 133
SER A 131
LEU A  39
HIS A 139
GLU A  98
 None
 1.22A 1mmtA-1sfrA:
undetectable		 1mmtA-1sfrA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.92A 1ng8A-1sfrA:
undetectable		 1ng8A-1sfrA:
4.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.92A 1ng8B-1sfrA:
undetectable		 1ng8B-1sfrA:
4.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.69A 1nrmA-1sfrA:
undetectable		 1nrmA-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.69A 1nrmB-1sfrA:
undetectable		 1nrmB-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.88A 1nruA-1sfrA:
undetectable		 1nruA-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.89A 1nruB-1sfrA:
undetectable		 1nruB-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.65A 1nt5A-1sfrA:
undetectable		 1nt5A-1sfrA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.65A 1nt5B-1sfrA:
undetectable		 1nt5B-1sfrA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.63A 1nt6A-1sfrA:
undetectable		 1nt6A-1sfrA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.63A 1nt6B-1sfrA:
undetectable		 1nt6B-1sfrA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.73A 1w5uC-1sfrA:
undetectable
1w5uD-1sfrA:
undetectable		 1w5uC-1sfrA:
6.90
1w5uD-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		4 / 7 TYR A 174
TYR A  95
ASP A  40
ASP A  52
 None
 1.10A 2g72B-1sfrA:
undetectable		 2g72B-1sfrA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 TRP A  51
ALA A 129
VAL A 123
 None
 0.59A 2izqA-1sfrA:
undetectable
2izqB-1sfrA:
undetectable		 2izqA-1sfrA:
6.90
2izqB-1sfrA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 9 PHE A 240
ALA A 243
TYR A 244
GLY A 198
ILE A 201
 None
 1.12A 2v7bA-1sfrA:
2.3		 2v7bA-1sfrA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 PRO A  71
GLU A  98
TYR A  79
 None
 0.82A 2zmbA-1sfrA:
undetectable		 2zmbA-1sfrA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 278
ALA A 284
ARG A 280
SER A  33
ALA A 121
 None
 1.16A 3axtA-1sfrA:
undetectable		 3axtA-1sfrA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		4 / 4 SER A 150
GLY A 151
GLY A 212
GLY A 231
 None
 0.84A 3bogB-1sfrA:
0.0
3bogD-1sfrA:
0.0		 3bogB-1sfrA:
undetectable
3bogD-1sfrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 187
ASN A 191
PRO A 155
PRO A 161
 None
 0.77A 3fxrA-1sfrA:
undetectable		 3fxrA-1sfrA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.64A 3l8lA-1sfrA:
undetectable
3l8lB-1sfrA:
undetectable		 3l8lA-1sfrA:
6.90
3l8lB-1sfrA:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 129
VAL A 123
TRP A  51
 None
 0.71A 3l8lC-1sfrA:
undetectable
3l8lD-1sfrA:
undetectable		 3l8lC-1sfrA:
6.90
3l8lD-1sfrA:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		6 / 12 ALA A 243
PHE A 240
ASN A 203
ILE A 137
LEU A 133
VAL A 207
 None
 1.47A 3rukA-1sfrA:
undetectable		 3rukA-1sfrA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		4 / 8 ASN A 203
GLN A 141
LYS A 116
THR A 118
 None
 1.43A 4d1yA-1sfrA:
2.4
4d1yB-1sfrA:
2.9		 4d1yA-1sfrA:
23.24
4d1yB-1sfrA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 PHE A 256
TYR A 266
ALA A 269
GLY A 268
LEU A 271
 None
 1.20A 4oadA-1sfrA:
0.0		 4oadA-1sfrA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  88
GLY A 173
SER A  76
ALA A  90
ARG A  20
 None
 1.03A 4qtuB-1sfrA:
undetectable		 4qtuB-1sfrA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  88
GLY A 173
SER A  76
ALA A  90
ARG A  20
 None
 0.99A 4qtuD-1sfrA:
undetectable		 4qtuD-1sfrA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 167
GLY A 160
PHE A  78
GLY A 151
LEU A 229
 None
 1.24A 4uilH-1sfrA:
undetectable
4uilL-1sfrA:
undetectable		 4uilH-1sfrA:
20.51
4uilL-1sfrA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		4 / 5 VAL A  72
ASP A  40
PHE A  48
GLY A  50
 None
 1.26A 4xp6A-1sfrA:
0.0		 4xp6A-1sfrA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 160
TYR A  95
GLY A  88
PHE A  78
THR A 162
 None
 1.18A 5eskA-1sfrA:
undetectable		 5eskA-1sfrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 160
TYR A  95
GLY A  88
PHE A  78
THR A 162
 None
 1.19A 5eslA-1sfrA:
undetectable		 5eslA-1sfrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		4 / 6 GLY A  88
GLN A  93
TYR A  95
TYR A 174
 None
 1.00A 6ag0A-1sfrA:
undetectable		 6ag0A-1sfrA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		4 / 6 GLY A  88
GLN A  93
TYR A  95
TYR A 174
 None
 0.96A 6ag0C-1sfrA:
undetectable		 6ag0C-1sfrA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1sfr ANTIGEN 85-A
(Mycobacterium
tuberculosis) 		3 / 3 LEU A 200
GLY A 252
PHE A 256
 None
 0.57A 6exiC-1sfrA:
3.7		 6exiC-1sfrA:
16.47