SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CL5_B_SAMB1217_1 (CATECHOL O-METHYLTRANSFERASE)	1sg1	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 (Rattus norvegicus)	4 / 6	SER X 127 SER X 109 GLN X 111 ASP X 134	None	1.39A	2cl5B-1sg1X: undetectable	2cl5B-1sg1X: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZVJ_A_SAMA301_1 (CATECHOL O-METHYLTRANSFERASE)	1sg1	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 (Rattus norvegicus)	4 / 6	SER X 127 SER X 109 GLN X 111 ASP X 134	None	1.39A	2zvjA-1sg1X: 0.0	2zvjA-1sg1X: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_D_ACTD502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	1sg1	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 (Rattus norvegicus)	3 / 3	GLY X 30 THR X 10 ASN X 32	None	0.69A	3v4tD-1sg1X: undetectable	3v4tD-1sg1X: 17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHR_B_SAMB303_1 (CATECHOL O-METHYLTRANSFERASE)	1sg1	TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 (Rattus norvegicus)	4 / 5	SER X 127 SER X 109 GLN X 111 ASP X 134	None	1.40A	5fhrB-1sg1X: undetectable	5fhrB-1sg1X: 18.01

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CL5_B_SAMB1217_1","CATECHOL O-METHYLTRANSFERASE","1sg1","TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16","Rattus norvegicus",4,"SER X 127;SER X 109;GLN X 111;ASP X 134","None","1.39A","2cl5B-1sg1X:undetectable","2cl5B-1sg1X:19.37"],["2ZVJ_A_SAMA301_1","CATECHOL O-METHYLTRANSFERASE","1sg1","TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16","Rattus norvegicus",4,"SER X 127;SER X 109;GLN X 111;ASP X 134","None","1.39A","2zvjA-1sg1X:0.0","2zvjA-1sg1X:19.37"],["3V4T_D_ACTD502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","1sg1","TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16","Rattus norvegicus",3,"GLY X  30;THR X  10;ASN X  32","None","0.69A","3v4tD-1sg1X:undetectable","3v4tD-1sg1X:17.62"],["5FHR_B_SAMB303_1","CATECHOL O-METHYLTRANSFERASE","1sg1","TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16","Rattus norvegicus",4,"SER X 127;SER X 109;GLN X 111;ASP X 134","None","1.40A","5fhrB-1sg1X:undetectable","5fhrB-1sg1X:18.01"]]