SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sg3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 6 ASN A  20
ALA A  22
GLY A 182
TYR A 181
 None
 1.12A 1gfzA-1sg3A:
undetectable		 1gfzA-1sg3A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 9 LEU A  30
VAL A 184
TYR A 200
GLY A 204
LEU A 223
 None
 1.49A 1ikvA-1sg3A:
0.0		 1ikvA-1sg3A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 269
ASN A 272
ILE A 329
GLY A 333
 None
 1.06A 1oniA-1sg3A:
undetectable
1oniB-1sg3A:
undetectable		 1oniA-1sg3A:
17.48
1oniB-1sg3A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 269
ASN A 272
ILE A 329
GLY A 333
 None
 1.11A 1oniD-1sg3A:
undetectable
1oniF-1sg3A:
undetectable		 1oniD-1sg3A:
17.48
1oniF-1sg3A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 8 ALA A 199
ILE A 262
ILE A 259
GLY A 342
ILE A 195
 None
 1.26A 1sh9A-1sg3A:
undetectable		 1sh9A-1sg3A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 199
VAL A 325
ILE A 262
ALA A 248
ILE A 250
 None
 0.86A 2idwA-1sg3A:
undetectable		 2idwA-1sg3A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  48
ASN A 108
GLN A 147
ILE A 100
 None
 1.19A 2jn3A-1sg3A:
undetectable		 2jn3A-1sg3A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 222
ARG A 339
ALA A 205
ILE A 338
 None
 1.06A 2qhfA-1sg3A:
undetectable		 2qhfA-1sg3A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 165
PHE A 141
GLY A  97
GLY A  98
 None
 0.82A 2qx4A-1sg3A:
undetectable
2qx4B-1sg3A:
undetectable		 2qx4A-1sg3A:
23.23
2qx4B-1sg3A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 8 GLY A  27
ILE A  95
PHE A 141
PHE A 178
 None
 0.97A 3ko0K-1sg3A:
undetectable
3ko0S-1sg3A:
undetectable		 3ko0K-1sg3A:
15.34
3ko0S-1sg3A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 5 VAL A  25
ILE A  16
MET A   1
ARG A 161
 None
 1.17A 3pyyB-1sg3A:
undetectable		 3pyyB-1sg3A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 6 ALA A 207
GLY A 204
LEU A 222
VAL A 201
 None
 1.06A 4dubA-1sg3A:
undetectable		 4dubA-1sg3A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 7 VAL A 279
ILE A 338
ARG A 339
ILE A 250
ALA A 199
 None
 1.29A 4lv9A-1sg3A:
undetectable		 4lv9A-1sg3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 119
ILE A  95
ILE A 137
ALA A 117
 None
 0.91A 4lv9B-1sg3A:
undetectable		 4lv9B-1sg3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 178
ILE A 100
ASP A  69
GLY A  70
 None
 0.91A 5h3aA-1sg3A:
undetectable		 5h3aA-1sg3A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  49
GLY A  32
LEU A  48
GLU A  46
VAL A  84
 None
 1.17A 5hw4A-1sg3A:
undetectable		 5hw4A-1sg3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 11 ILE A  49
GLY A  32
LEU A  48
GLU A  46
VAL A  84
 None
 1.23A 5hw4B-1sg3A:
undetectable		 5hw4B-1sg3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  49
GLY A  32
LEU A  48
GLU A  46
VAL A  84
 None
 1.17A 5hw4C-1sg3A:
2.1		 5hw4C-1sg3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 10 ASP A  24
ALA A 117
ILE A 165
GLY A  97
VAL A 138
 None
 1.03A 5i6xA-1sg3A:
undetectable		 5i6xA-1sg3A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 10 VAL A  90
GLY A  89
GLY A  32
ILE A 165
ALA A  93
 None
 1.04A 5vm8B-1sg3A:
undetectable		 5vm8B-1sg3A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		4 / 4 ASP A 212
SER A 211
ASP A 246
HIS A 244
 None
 1.30A 5wyqB-1sg3A:
undetectable		 5wyqB-1sg3A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 1sg3 ALLANTOICASE
(Saccharomyces
cerevisiae) 		5 / 9 THR A 236
GLY A 333
GLY A 334
TRP A 247
VAL A 264
 None
 1.47A 6gnfA-1sg3A:
undetectable		 6gnfA-1sg3A:
20.55