SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sgm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1sgm PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YXAF
(Bacillus
subtilis) 		5 / 12 VAL A  66
PHE A 128
ASN A 157
GLY A 163
ILE A 164
 None
 1.19A 2dcfA-1sgmA:
0.0		 2dcfA-1sgmA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1sgm PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YXAF
(Bacillus
subtilis) 		3 / 3 LEU A 155
MET A 159
MET A 125
 None
 0.88A 2vavF-1sgmA:
undetectable		 2vavF-1sgmA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 1sgm PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YXAF
(Bacillus
subtilis) 		5 / 12 ALA A  58
SER A  19
GLY A  23
HIS A  25
THR A  27
 None
 1.44A 2xffA-1sgmA:
undetectable		 2xffA-1sgmA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 1sgm PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR YXAF
(Bacillus
subtilis) 		3 / 3 THR A  60
ASN A  49
PHE A  47
 None
 0.74A 4pd9A-1sgmA:
0.8		 4pd9A-1sgmA:
20.30