SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1shk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 1shk SHIKIMATE KINASE
(Dickeya
chrysanthemi) 		5 / 10 GLY A  79
LEU A 142
TYR A 143
THR A  77
GLY A  78
 None
 1.34A 1kvlA-1shkA:
undetectable		 1kvlA-1shkA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 1shk SHIKIMATE KINASE
(Dickeya
chrysanthemi) 		4 / 6 LEU A 164
MET A 168
LEU A 170
MET A   7
 None
 0.94A 2kuhA-1shkA:
undetectable		 2kuhA-1shkA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1shk SHIKIMATE KINASE
(Dickeya
chrysanthemi) 		3 / 3 ALA A 141
VAL A   8
TYR A  99
 None
 0.63A 5zmqH-1shkA:
undetectable		 5zmqH-1shkA:
22.39