SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1shw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1shw EPHRIN TYPE-B
RECEPTOR 2
(Mus
musculus) 		4 / 4 ILE B 286
LEU B 321
VAL B 296
ILE B 294
 None
 0.93A 1fm6D-1shwB:
undetectable		 1fm6D-1shwB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 1shw EPHRIN TYPE-B
RECEPTOR 2
(Mus
musculus) 		6 / 12 GLY B 290
ALA B 291
VAL B 400
ILE B 286
GLY B 381
ILE B 294
 None
 1.49A 2r5pB-1shwB:
undetectable		 2r5pB-1shwB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 1shw EPHRIN TYPE-B
RECEPTOR 2
(Mus
musculus) 		3 / 3 MET B 244
GLN B 387
TYR B 322
 None
 1.06A 4udcA-1shwB:
undetectable		 4udcA-1shwB:
21.35