SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1sj5 CONSERVED
HYPOTHETICAL PROTEIN
TM0160
(Thermotoga
maritima) 		4 / 4 THR A  57
LEU A  61
VAL A  64
LEU A  68
 None
 0.80A 1fbmD-1sj5A:
undetectable		 1fbmD-1sj5A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1sj5 CONSERVED
HYPOTHETICAL PROTEIN
TM0160
(Thermotoga
maritima) 		4 / 4 ILE A 118
LEU A  22
VAL A  20
ILE A  35
 None
 0.88A 1fm6D-1sj5A:
undetectable		 1fm6D-1sj5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1sj5 CONSERVED
HYPOTHETICAL PROTEIN
TM0160
(Thermotoga
maritima) 		3 / 3 THR A  57
LEU A  61
VAL A  64
 None
 0.49A 1mz9E-1sj5A:
undetectable		 1mz9E-1sj5A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1sj5 CONSERVED
HYPOTHETICAL PROTEIN
TM0160
(Thermotoga
maritima) 		4 / 5 ILE A 139
SER A 130
ARG A   2
LEU A  31
 None
 0.89A 1y0xX-1sj5A:
undetectable		 1y0xX-1sj5A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1sj5 CONSERVED
HYPOTHETICAL PROTEIN
TM0160
(Thermotoga
maritima) 		4 / 8 ILE A  77
LEU A 106
LEU A  89
ILE A  91
 None
 0.88A 4r38D-1sj5A:
undetectable		 4r38D-1sj5A:
20.23