SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sjj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1sjj ACTININ
(Gallus
gallus) 		4 / 6 LEU A 505
ALA A 426
LEU A 428
SER A 429
 None
 1.23A 1tyrA-1sjjA:
undetectable		 1tyrA-1sjjA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1sjj ACTININ
(Gallus
gallus) 		3 / 3 ASP A 224
VAL A 229
PRO A 202
 None
 0.79A 2avvA-1sjjA:
undetectable		 2avvA-1sjjA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 1sjj ACTININ
(Gallus
gallus) 		4 / 8 SER A  74
LEU A  66
LEU A  98
LEU A 108
 None
 0.99A 2bfpC-1sjjA:
undetectable		 2bfpC-1sjjA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1sjj ACTININ
(Gallus
gallus) 		3 / 3 ARG A 476
ASN A 486
THR A 411
 None
 0.87A 2q63A-1sjjA:
undetectable		 2q63A-1sjjA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 1sjj ACTININ
(Gallus
gallus) 		3 / 3 LEU A 848
PRO A 849
ARG A 859
 None
 0.51A 2qd5A-1sjjA:
undetectable		 2qd5A-1sjjA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1sjj ACTININ
(Gallus
gallus) 		5 / 10 ILE A 228
ILE A 239
ILE A 167
PHE A 180
THR A 231
 None
 1.20A 2w9sC-1sjjA:
undetectable		 2w9sC-1sjjA:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 11 GLY A 105
ARG A 134
ILE A 101
LEU A 108
THR A 130
 None
 1.37A 3bexC-1sjjA:
undetectable
3bexD-1sjjA:
undetectable		 3bexC-1sjjA:
14.41
3bexD-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 10 LEU A 108
THR A 130
GLY A 105
ARG A 134
ILE A 101
 None
 1.38A 3bexC-1sjjA:
undetectable
3bexD-1sjjA:
undetectable		 3bexC-1sjjA:
14.41
3bexD-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 10 GLY A 105
ARG A 134
ILE A 101
LEU A 108
THR A 130
 None
 1.39A 3bexE-1sjjA:
undetectable
3bexF-1sjjA:
undetectable		 3bexE-1sjjA:
14.41
3bexF-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 11 LEU A 108
THR A 130
GLY A 105
ARG A 134
ILE A 101
 None
 1.38A 3bexE-1sjjA:
undetectable
3bexF-1sjjA:
undetectable		 3bexE-1sjjA:
14.41
3bexF-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 11 GLY A 105
ARG A 134
ILE A 101
LEU A 108
THR A 130
 None
 1.37A 3bf1A-1sjjA:
undetectable
3bf1B-1sjjA:
undetectable		 3bf1A-1sjjA:
14.41
3bf1B-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 11 GLY A 105
ARG A 134
ILE A 101
LEU A 108
THR A 130
 None
 1.39A 3bf1C-1sjjA:
undetectable
3bf1D-1sjjA:
undetectable		 3bf1C-1sjjA:
14.41
3bf1D-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 11 LEU A 108
THR A 130
GLY A 105
ARG A 134
ILE A 101
 None
 1.37A 3bf1C-1sjjA:
undetectable
3bf1D-1sjjA:
undetectable		 3bf1C-1sjjA:
14.41
3bf1D-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1sjj ACTININ
(Gallus
gallus) 		5 / 11 LEU A 108
THR A 130
GLY A 105
ARG A 134
ILE A 101
 None
 1.40A 3bf1E-1sjjA:
undetectable
3bf1F-1sjjA:
undetectable		 3bf1E-1sjjA:
14.41
3bf1F-1sjjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 1sjj ACTININ
(Gallus
gallus) 		4 / 7 GLY A 765
PHE A 756
CYH A 769
PHE A 772
 None
 1.13A 3ko0D-1sjjA:
6.0
3ko0E-1sjjA:
6.2		 3ko0D-1sjjA:
7.06
3ko0E-1sjjA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1sjj ACTININ
(Gallus
gallus) 		4 / 5 ILE A 172
VAL A 229
LEU A 206
ASP A 176
 None
 1.17A 3wzdA-1sjjA:
undetectable		 3wzdA-1sjjA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1sjj ACTININ
(Gallus
gallus) 		4 / 6 LEU A  69
LYS A  65
LEU A  46
GLU A  54
 None
 1.14A 4f3tA-1sjjA:
undetectable		 4f3tA-1sjjA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1sjj ACTININ
(Gallus
gallus) 		3 / 3 GLU A  58
ASP A  62
ASP A 118
 None
 0.79A 4gc9A-1sjjA:
undetectable		 4gc9A-1sjjA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1sjj ACTININ
(Gallus
gallus) 		3 / 3 GLU A 630
ARG A 633
HIS A 706
 None
 0.34A 4kf9A-1sjjA:
undetectable		 4kf9A-1sjjA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1sjj ACTININ
(Gallus
gallus) 		4 / 8 LEU A 288
ASP A 364
ASN A 367
ALA A 368
 None
 0.92A 4zbqA-1sjjA:
undetectable		 4zbqA-1sjjA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1sjj ACTININ
(Gallus
gallus) 		4 / 6 LEU A 505
ALA A 426
LEU A 428
SER A 429
 None
 1.22A 5a6iA-1sjjA:
undetectable		 5a6iA-1sjjA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 1sjj ACTININ
(Gallus
gallus) 		4 / 8 SER A 173
GLN A 156
MET A 355
THR A 159
 None
 1.20A 5u6nA-1sjjA:
undetectable		 5u6nA-1sjjA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 1sjj ACTININ
(Gallus
gallus) 		5 / 9 ASN A 261
ILE A 131
ILE A 132
GLU A  71
ILE A 128
 None
 1.23A 6hloA-1sjjA:
3.2		 6hloA-1sjjA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1sjj ACTININ
(Gallus
gallus) 		3 / 3 ARG A 392
LEU A 396
PHE A 400
 None
 0.67A 6nknP-1sjjA:
2.6		 6nknP-1sjjA:
13.54