SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QQT_A_AINA596_1 (LACTOPEROXIDASE)	1sjw	NOGALONIC ACID METHYL ESTER CYCLASE (Streptomyces nogalater)	4 / 6	HIS A 39 PHE A 125 GLN A 105 PRO A 123	None NGV A 333 (-4.5A) NGV A 333 (-2.8A) NGV A 333 (-4.5A)	1.04A	2qqtA-1sjwA: undetectable	2qqtA-1sjwA: 12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VJ1_A_BEZA1303_0 (SARS CORONAVIRUS MAIN PROTEINASE)	1sjw	NOGALONIC ACID METHYL ESTER CYCLASE (Streptomyces nogalater)	3 / 3	HIS A 107 MET A 109 MET A 11	None	1.41A	2vj1A-1sjwA: undetectable	2vj1A-1sjwA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1339_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1sjw	NOGALONIC ACID METHYL ESTER CYCLASE (Streptomyces nogalater)	3 / 3	ASP A 121 HIS A 119 HIS A 107	NGV A 333 (-3.5A) None None	0.70A	2xxgC-1sjwA: undetectable	2xxgC-1sjwA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZSE_A_PAUA600_0 (PANTOTHENATE KINASE)	1sjw	NOGALONIC ACID METHYL ESTER CYCLASE (Streptomyces nogalater)	4 / 7	TYR A 31 PHE A 48 PHE A 15 ILE A 116	None None NGV A 333 ( 4.4A) None	1.01A	2zseA-1sjwA: 0.0	2zseA-1sjwA: 19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GCL_A_AINA609_1 (LACTOPEROXIDASE)	1sjw	NOGALONIC ACID METHYL ESTER CYCLASE (Streptomyces nogalater)	4 / 6	HIS A 39 PHE A 125 GLN A 105 PRO A 123	None NGV A 333 (-4.5A) NGV A 333 (-2.8A) NGV A 333 (-4.5A)	1.06A	3gclA-1sjwA: undetectable	3gclA-1sjwA: 12.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QQT_A_AINA596_1","LACTOPEROXIDASE","1sjw","NOGALONIC ACID METHYL ESTER CYCLASE","Streptomyces nogalater",4,"HIS A  39;PHE A 125;GLN A 105;PRO A 123","None;NGV A 333 (-4.5A);NGV A 333 (-2.8A);NGV A 333 (-4.5A)","1.04A","2qqtA-1sjwA:undetectable","2qqtA-1sjwA:12.43"],["2VJ1_A_BEZA1303_0","SARS CORONAVIRUS MAIN PROTEINASE","1sjw","NOGALONIC ACID METHYL ESTER CYCLASE","Streptomyces nogalater",3,"HIS A 107;MET A 109;MET A  11","None","1.41A","2vj1A-1sjwA:undetectable","2vj1A-1sjwA:20.07"],["2XXG_C_CUC1339_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1sjw","NOGALONIC ACID METHYL ESTER CYCLASE","Streptomyces nogalater",3,"ASP A 121;HIS A 119;HIS A 107","NGV A 333 (-3.5A);None;None","0.70A","2xxgC-1sjwA:undetectable","2xxgC-1sjwA:18.26"],["2ZSE_A_PAUA600_0","PANTOTHENATE KINASE","1sjw","NOGALONIC ACID METHYL ESTER CYCLASE","Streptomyces nogalater",4,"TYR A  31;PHE A  48;PHE A  15;ILE A 116","None;None;NGV A 333 ( 4.4A);None","1.01A","2zseA-1sjwA:0.0","2zseA-1sjwA:19.61"],["3GCL_A_AINA609_1","LACTOPEROXIDASE","1sjw","NOGALONIC ACID METHYL ESTER CYCLASE","Streptomyces nogalater",4,"HIS A  39;PHE A 125;GLN A 105;PRO A 123","None;NGV A 333 (-4.5A);NGV A 333 (-2.8A);NGV A 333 (-4.5A)","1.06A","3gclA-1sjwA:undetectable","3gclA-1sjwA:12.43"]]