SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sk4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 1sk4 PEPTIDOGLYCAN
RECOGNITION PROTEIN
I-ALPHA
(Homo
sapiens) 		4 / 5 PHE A 281
ALA A 210
GLY A 211
TYR A 280
 None
 1.22A 3bcrA-1sk4A:
undetectable		 3bcrA-1sk4A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1sk4 PEPTIDOGLYCAN
RECOGNITION PROTEIN
I-ALPHA
(Homo
sapiens) 		4 / 8 ILE A 275
PRO A 179
ASN A 180
GLY A 257
 None
 0.92A 3em0B-1sk4A:
undetectable		 3em0B-1sk4A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 1sk4 PEPTIDOGLYCAN
RECOGNITION PROTEIN
I-ALPHA
(Homo
sapiens) 		4 / 6 ASP A 270
ASN A 269
ALA A 272
TYR A 203
 None
 0.99A 4mdaA-1sk4A:
0.0		 4mdaA-1sk4A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1sk4 PEPTIDOGLYCAN
RECOGNITION PROTEIN
I-ALPHA
(Homo
sapiens) 		3 / 3 LEU A 245
ASP A 296
ILE A 298
 None
 0.65A 6dh0B-1sk4A:
undetectable		 6dh0B-1sk4A:
17.58