SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 188
GLY A  98
ASP A  99
 None
 0.54A 1kf6A-1sk7A:
undetectable
1kf6B-1sk7A:
undetectable		 1kf6A-1sk7A:
16.52
1kf6B-1sk7A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 138
PHE A  45
ARG A 154
 None
 0.85A 1xdkB-1sk7A:
undetectable		 1xdkB-1sk7A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 138
PHE A  45
ARG A 154
 None
 0.85A 1xdkF-1sk7A:
undetectable		 1xdkF-1sk7A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 8 LYS A  34
PHE A 197
LEU A 193
PHE A 189
 None
None
None
HEM  A 300 (-3.7A)
 0.87A 2eilC-1sk7A:
undetectable
2eilJ-1sk7A:
undetectable		 2eilC-1sk7A:
21.29
2eilJ-1sk7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 8 LYS A  34
PHE A 197
LEU A 193
PHE A 189
 None
None
None
HEM  A 300 (-3.7A)
 0.99A 2eilP-1sk7A:
undetectable
2eilW-1sk7A:
undetectable		 2eilP-1sk7A:
21.29
2eilW-1sk7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 7 LYS A  34
PHE A 197
LEU A 193
PHE A 189
 None
None
None
HEM  A 300 (-3.7A)
 0.91A 2eimP-1sk7A:
1.7
2eimW-1sk7A:
undetectable		 2eimP-1sk7A:
21.29
2eimW-1sk7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  54
TYR A  53
GLN A  56
 None
 0.70A 2wekA-1sk7A:
undetectable		 2wekA-1sk7A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 7 LYS A  34
PHE A 197
LEU A 193
PHE A 189
 None
None
None
HEM  A 300 (-3.7A)
 0.98A 3asnP-1sk7A:
2.1
3asnW-1sk7A:
undetectable		 3asnP-1sk7A:
21.29
3asnW-1sk7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 8 LYS A  34
PHE A 197
LEU A 193
PHE A 189
 None
None
None
HEM  A 300 (-3.7A)
 0.96A 3asoC-1sk7A:
undetectable
3asoJ-1sk7A:
undetectable		 3asoC-1sk7A:
21.29
3asoJ-1sk7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 7 LYS A  34
PHE A 197
LEU A 193
PHE A 189
 None
None
None
HEM  A 300 (-3.7A)
 1.01A 3asoP-1sk7A:
undetectable
3asoW-1sk7A:
undetectable		 3asoP-1sk7A:
21.29
3asoW-1sk7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 110
GLU A 174
LEU A  68
LEU A  71
ILE A 164
 None
 1.45A 4xtaA-1sk7A:
undetectable		 4xtaA-1sk7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		5 / 10 ARG A  80
ALA A  84
LEU A 147
LEU A  54
ALA A  51
 None
 1.18A 4zbrA-1sk7A:
undetectable		 4zbrA-1sk7A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  32
LEU A 192
GLY A 190
LEU A 193
ALA A  51
 None
 1.03A 5dqfA-1sk7A:
undetectable		 5dqfA-1sk7A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 109
LEU A  68
ARG A 188
 None
 0.63A 5hnzB-1sk7A:
undetectable		 5hnzB-1sk7A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 7 LYS A  34
PHE A 197
LEU A 193
PHE A 189
 None
None
None
HEM  A 300 (-3.7A)
 0.89A 5x1fP-1sk7A:
1.8
5x1fW-1sk7A:
undetectable		 5x1fP-1sk7A:
21.29
5x1fW-1sk7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  62
LYS A 180
GLU A 111
LEU A 107
 None
 1.36A 5xooA-1sk7A:
undetectable		 5xooA-1sk7A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1sk7 HYPOTHETICAL PROTEIN
PA-HO
(Pseudomonas
aeruginosa) 		4 / 8 GLY A  74
GLY A 157
SER A 160
ALA A 163
 None
 0.80A 6hu9H-1sk7A:
undetectable
6hu9e-1sk7A:
undetectable		 6hu9H-1sk7A:
16.67
6hu9e-1sk7A:
23.00