SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ska'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		3 / 3 GLU A 148
ALA A 172
SER A 174
 None
 0.62A 1errB-1skaA:
undetectable		 1errB-1skaA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 ASP A 311
ASN A 184
GLY A 190
GLY A 293
 None
NAG  A 503 ( 1.8A)
None
None
 0.78A 1me7A-1skaA:
undetectable		 1me7A-1skaA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.79A 1v55N-1skaA:
undetectable
1v55W-1skaA:
undetectable		 1v55N-1skaA:
19.89
1v55W-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 12 ALA A 170
GLY A 117
GLY A 153
ILE A 151
ASP A  12
 None
 0.92A 1x1aA-1skaA:
undetectable		 1x1aA-1skaA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 5 LEU A 113
GLY A  60
HIS A  59
PHE A  31
 None
 0.91A 1xf1A-1skaA:
undetectable		 1xf1A-1skaA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 6 LEU A 113
GLY A  60
HIS A  59
PHE A  31
 None
 0.89A 1xf1B-1skaA:
undetectable		 1xf1B-1skaA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 12 GLY A 289
LEU A 187
ASP A 188
ASP A 335
SER A 314
 None
 1.31A 2b9eA-1skaA:
undetectable		 2b9eA-1skaA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.76A 2eijN-1skaA:
0.0
2eijW-1skaA:
0.0		 2eijN-1skaA:
19.89
2eijW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 7 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.74A 2eikA-1skaA:
0.0
2eikJ-1skaA:
undetectable		 2eikA-1skaA:
19.89
2eikJ-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.76A 2eikN-1skaA:
0.0
2eikW-1skaA:
undetectable		 2eikN-1skaA:
19.89
2eikW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.78A 2eilN-1skaA:
0.0
2eilW-1skaA:
undetectable		 2eilN-1skaA:
19.89
2eilW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.79A 2einA-1skaA:
undetectable
2einJ-1skaA:
undetectable		 2einA-1skaA:
19.89
2einJ-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.87A 3abkA-1skaA:
undetectable
3abkJ-1skaA:
undetectable		 3abkA-1skaA:
19.89
3abkJ-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.84A 3ablN-1skaA:
0.1
3ablW-1skaA:
undetectable		 3ablN-1skaA:
19.89
3ablW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.82A 3abmN-1skaA:
undetectable
3abmW-1skaA:
undetectable		 3abmN-1skaA:
19.89
3abmW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.81A 3asnN-1skaA:
0.4
3asnW-1skaA:
0.0		 3asnN-1skaA:
19.89
3asnW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.83A 3asoN-1skaA:
undetectable
3asoW-1skaA:
undetectable		 3asoN-1skaA:
19.89
3asoW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 6 SER A 116
PHE A 120
TYR A 385
PRO A 133
 None
 1.47A 3jqaB-1skaA:
undetectable		 3jqaB-1skaA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		3 / 3 LYS A 222
PRO A 225
LYS A  87
 None
 1.45A 4dv7L-1skaA:
0.0		 4dv7L-1skaA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 5 PRO A 178
GLY A 139
ASP A 311
ASP A 188
 None
 0.94A 4n48B-1skaA:
undetectable		 4n48B-1skaA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 7 LEU A 402
LEU A 300
LEU A 410
ILE A 345
 None
 0.98A 4okwA-1skaA:
undetectable		 4okwA-1skaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 10 THR A 106
ALA A 247
THR A 249
ALA A 252
THR A 245
 None
 1.32A 4qw3H-1skaA:
undetectable
4qw3I-1skaA:
0.0		 4qw3H-1skaA:
18.65
4qw3I-1skaA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 11 THR A 106
ALA A 247
THR A 249
ALA A 252
THR A 245
 None
 1.31A 4qw3V-1skaA:
0.0
4qw3W-1skaA:
undetectable		 4qw3V-1skaA:
18.65
4qw3W-1skaA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 12 THR A 106
ALA A 247
THR A 249
ALA A 252
THR A 245
 None
 1.32A 5d0xH-1skaA:
undetectable
5d0xI-1skaA:
undetectable		 5d0xH-1skaA:
18.65
5d0xI-1skaA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		3 / 3 THR A 297
ALA A 433
ASN A 298
 None
 0.63A 5ersA-1skaA:
undetectable		 5ersA-1skaA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 12 PRO A 178
GLY A 139
ASP A 311
GLY A 295
ASP A 188
 None
 1.03A 5wwsA-1skaA:
undetectable		 5wwsA-1skaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 12 PRO A 178
GLY A 139
ASP A 311
GLY A 295
ASP A 188
 None
 1.03A 5wwsB-1skaA:
undetectable		 5wwsB-1skaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.82A 5xdxN-1skaA:
0.0
5xdxW-1skaA:
0.0		 5xdxN-1skaA:
19.89
5xdxW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.81A 5zcpN-1skaA:
0.6
5zcpW-1skaA:
undetectable		 5zcpN-1skaA:
19.89
5zcpW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.83A 5zcqN-1skaA:
0.0
5zcqW-1skaA:
undetectable		 5zcqN-1skaA:
19.89
5zcqW-1skaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 12 VAL A  76
VAL A 234
LEU A 237
PHE A 258
PHE A  86
 None
 1.04A 6drzA-1skaA:
0.0		 6drzA-1skaA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1ska 3-PHYTASE A
(Aspergillus
fumigatus) 		5 / 12 VAL A  76
VAL A 234
PHE A 258
PHE A  86
VAL A 227
 None
 1.05A 6drzA-1skaA:
0.0		 6drzA-1skaA:
22.13