SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sky'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 7 ALA B 197
SER B 227
THR B 225
VAL B 223
 None
 0.95A 1dvxB-1skyB:
undetectable		 1dvxB-1skyB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 4 LYS B 496
LEU B 464
ALA B 493
LEU B 435
 None
 1.40A 1f86B-1skyB:
0.0		 1f86B-1skyB:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1sky F1-ATPASE
F1-ATPASE
(Bacillus
sp.
PS3;
Bacillus
sp.
PS3) 		5 / 12 PHE B 349
THR B 207
ILE E 358
ALA E 327
SER E 351
 None
 1.32A 1fm4A-1skyB:
0.0		 1fm4A-1skyB:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 8 HIS E 119
LEU E 230
ALA E 229
LEU E 233
 None
 0.86A 1hwiD-1skyE:
0.0		 1hwiD-1skyE:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 7 VAL B  74
LEU B 276
LEU B 273
ALA E 282
 None
 0.83A 1j8uA-1skyB:
undetectable		 1j8uA-1skyB:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 ILE E 134
LEU E 135
GLY E 138
HIS E 179
ILE E 175
 None
 1.25A 1kyvB-1skyE:
3.0
1kyvC-1skyE:
2.9		 1kyvB-1skyE:
17.31
1kyvC-1skyE:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 ILE E 134
LEU E 135
GLY E 138
HIS E 179
ILE E 175
 None
 1.27A 1kyvD-1skyE:
2.7
1kyvE-1skyE:
undetectable		 1kyvD-1skyE:
17.31
1kyvE-1skyE:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 8 ILE B 222
GLY B 246
TYR B 248
GLU B 101
 None
 0.87A 1mrjA-1skyB:
undetectable		 1mrjA-1skyB:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 GLU B 320
THR B 321
LEU B 166
 None
 0.66A 1v8bC-1skyB:
2.5		 1v8bC-1skyB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 PRO B 110
PRO B 239
ILE B 260
GLY B 242
 None
 1.00A 2jkjD-1skyB:
undetectable		 2jkjD-1skyB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 PRO B 110
PRO B 239
ILE B 260
GLY B 242
 None
 0.99A 2jkjF-1skyB:
undetectable		 2jkjF-1skyB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 VAL B 208
ILE B 183
THR B 182
LEU B 257
VAL B 223
 None
 1.25A 2jn3A-1skyB:
undetectable		 2jn3A-1skyB:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 THR B 123
VAL B  97
VAL B 108
ILE B 222
VAL B 224
 None
 1.35A 2qboA-1skyB:
0.0		 2qboA-1skyB:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 GLU E 439
ILE E 440
GLY E 436
LYS E 444
 None
 1.11A 2qeuA-1skyE:
0.0
2qeuC-1skyE:
undetectable		 2qeuA-1skyE:
16.00
2qeuC-1skyE:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 ILE B 167
ILE B 183
THR B 182
LEU B 257
VAL B 223
 None
 1.06A 2qo5A-1skyB:
0.0		 2qo5A-1skyB:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 ILE B 150
ASP B 154
THR B 182
VAL B 178
PRO B 355
 None
 1.31A 2yzqA-1skyB:
undetectable		 2yzqA-1skyB:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 GLN E 278
THR E 280
HIS E 119
LEU E 230
 None
 1.34A 2zj0A-1skyE:
undetectable		 2zj0A-1skyE:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 ILE E 109
ARG E 114
MET E 235
THR E 234
 None
 1.29A 3abkN-1skyE:
1.0
3abkW-1skyE:
undetectable		 3abkN-1skyE:
23.01
3abkW-1skyE:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 6 THR B 148
GLN B 186
LEU B 316
LEU B 257
 None
 1.21A 3bgdA-1skyB:
2.5		 3bgdA-1skyB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 7 ALA B 197
SER B 227
THR B 225
VAL B 223
 None
 0.82A 3d2tA-1skyB:
undetectable		 3d2tA-1skyB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 6 ALA B 197
SER B 227
THR B 225
VAL B 223
 None
 0.69A 3d2tB-1skyB:
undetectable		 3d2tB-1skyB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 VAL B 417
THR B 416
ILE B 437
ALA B 155
ILE B 153
 None
 1.05A 3ddyA-1skyB:
5.5		 3ddyA-1skyB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 4 GLU E 170
GLY E 138
THR E 137
GLU E 136
 None
 1.03A 3e9xA-1skyE:
undetectable		 3e9xA-1skyE:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 ILE B  38
ILE B  75
VAL B  59
PRO B 110
LEU B  64
 None
 1.27A 3elzC-1skyB:
undetectable		 3elzC-1skyB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 8 ALA B 359
ILE B 357
ASN B 358
PRO B 355
 None
 1.00A 3fxrA-1skyB:
undetectable		 3fxrA-1skyB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 8 VAL E 184
VAL E  87
ILE E 292
GLY E 232
 None
 0.95A 3hjoA-1skyE:
undetectable		 3hjoA-1skyE:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1sky F1-ATPASE
F1-ATPASE
(Bacillus
sp.
PS3;
Bacillus
sp.
PS3) 		4 / 4 GLN B 113
PRO B 114
VAL B 115
GLU E 126
 None
 0.91A 3huoA-1skyB:
0.0		 3huoA-1skyB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 11 GLY E 187
PHE E 257
ASP E 252
ILE E 251
GLN E 304
 None
 1.31A 3id5B-1skyE:
undetectable		 3id5B-1skyE:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 11 GLY E 187
PHE E 257
ASP E 252
ILE E 251
GLN E 304
 None
 1.31A 3id5F-1skyE:
undetectable		 3id5F-1skyE:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 ILE B 357
ALA B 179
THR B 182
ILE B 159
VAL B 157
 None
 0.83A 3me6A-1skyB:
undetectable		 3me6A-1skyB:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 GLY B  35
ILE B  32
VAL B  31
 None
 0.49A 3nv6A-1skyB:
undetectable		 3nv6A-1skyB:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 7 ALA B 197
SER B 227
THR B 225
VAL B 223
 None
 0.86A 3ozkB-1skyB:
undetectable		 3ozkB-1skyB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 LEU E 248
LEU E 171
ILE E 292
GLN E 289
VAL E 344
 None
 1.28A 3w1wB-1skyE:
3.0		 3w1wB-1skyE:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 8 ILE B 184
ASN B 185
GLY B 149
ILE B 150
 None
 0.86A 3wxoA-1skyB:
0.0		 3wxoA-1skyB:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 6 ARG B 127
ILE B 194
VAL B 256
LEU B 313
 None
 1.04A 4em2A-1skyB:
undetectable		 4em2A-1skyB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 PRO E 346
ASP E 345
ILE E 340
VAL E 162
 None
None
None
SO4  E 474 (-4.1A)
 1.28A 4hytA-1skyE:
0.0		 4hytA-1skyE:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 8 ALA B 197
SER B 227
THR B 225
VAL B 223
 None
 0.85A 4ik7B-1skyB:
undetectable		 4ik7B-1skyB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 PHE B 460
THR B 441
PHE B 444
ILE B 436
 None
 1.12A 4jx1E-1skyB:
undetectable		 4jx1E-1skyB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 GLN B 113
LEU B  76
MET B  60
THR B  91
MET B  95
 None
 1.24A 4ojbA-1skyB:
undetectable		 4ojbA-1skyB:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 GLN B 113
LEU B  76
MET B  60
THR B  91
MET B  95
 None
 1.25A 4okxA-1skyB:
undetectable		 4okxA-1skyB:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 12 GLN B 113
LEU B  76
MET B  60
THR B  91
MET B  95
 None
 1.16A 4olmA-1skyB:
undetectable		 4olmA-1skyB:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 GLU E 190
ARG E 191
GLN E 259
 None
 0.92A 4rtbA-1skyE:
undetectable		 4rtbA-1skyE:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 7 PRO B 331
VAL B 334
ASN B 333
ILE B 337
ILE B 168
 None
 1.45A 5bmvC-1skyB:
3.0		 5bmvC-1skyB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 6 ALA B  41
THR B  30
VAL B  25
HIS B  42
 None
 1.00A 5eckA-1skyB:
2.1		 5eckA-1skyB:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 6 ALA B  41
THR B  30
VAL B  25
HIS B  42
 None
 1.01A 5eckD-1skyB:
undetectable		 5eckD-1skyB:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 8 ARG B 415
LEU B 440
LEU B 386
TYR B 389
LEU B 382
 None
 1.50A 5jqbA-1skyB:
undetectable
5jqbB-1skyB:
undetectable		 5jqbA-1skyB:
20.82
5jqbB-1skyB:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1sky F1-ATPASE
F1-ATPASE
(Bacillus
sp.
PS3;
Bacillus
sp.
PS3) 		4 / 5 GLU B 202
GLY B 199
SER B 229
GLY E 286
 None
 1.11A 5kprA-1skyB:
undetectable		 5kprA-1skyB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 ILE B 335
ILE B 326
PHE B 343
VAL B 334
GLU B 320
 None
 1.21A 5lg3F-1skyB:
undetectable		 5lg3F-1skyB:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 ILE B 335
ILE B 326
PHE B 343
VAL B 334
GLU B 320
 None
 1.18A 5lg3G-1skyB:
undetectable		 5lg3G-1skyB:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 ILE B 335
ILE B 326
PHE B 343
VAL B 334
GLU B 320
 None
 1.18A 5lg3H-1skyB:
0.1		 5lg3H-1skyB:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 9 ILE E 440
PHE E 453
VAL E 370
THR E 373
 None
 0.91A 5lg3I-1skyE:
0.0		 5lg3I-1skyE:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 7 GLY B 311
GLY B 309
SER B 141
ALA B 302
 None
 0.79A 5o96C-1skyB:
undetectable		 5o96C-1skyB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 6 ARG E 404
ARG E 405
ALA E 403
PHE E 408
 None
 1.40A 5odqA-1skyE:
undetectable		 5odqA-1skyE:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.60A 5qglA-1skyB:
undetectable		 5qglA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.64A 5qgnA-1skyB:
undetectable		 5qgnA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.69A 5qguA-1skyB:
undetectable		 5qguA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.65A 5qgvA-1skyB:
undetectable		 5qgvA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.68A 5qgwA-1skyB:
undetectable		 5qgwA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.65A 5qgxA-1skyB:
undetectable		 5qgxA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.65A 5qgyA-1skyB:
undetectable		 5qgyA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.66A 5qgzA-1skyB:
undetectable		 5qgzA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.67A 5qh0A-1skyB:
undetectable		 5qh0A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.64A 5qh1A-1skyB:
undetectable		 5qh1A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.66A 5qh2A-1skyB:
undetectable		 5qh2A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.67A 5qh3A-1skyB:
undetectable		 5qh3A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.66A 5qh4A-1skyB:
undetectable		 5qh4A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.64A 5qh5A-1skyB:
undetectable		 5qh5A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.66A 5qh7A-1skyB:
undetectable		 5qh7A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.71A 5qh9A-1skyB:
undetectable		 5qh9A-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.67A 5qhcA-1skyB:
undetectable		 5qhcA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.69A 5qheA-1skyB:
undetectable		 5qheA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.68A 5qhfA-1skyB:
undetectable		 5qhfA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.64A 5qhgA-1skyB:
undetectable		 5qhgA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		3 / 3 VAL B 224
VAL B 108
GLN B 113
 None
 0.67A 5qhhA-1skyB:
undetectable		 5qhhA-1skyB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 PRO B 233
ILE B  82
LEU B  76
LEU B  64
PHE B  55
 None
 1.30A 5tixB-1skyB:
undetectable		 5tixB-1skyB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		4 / 5 PRO B  78
VAL B  59
GLY B  72
VAL B  34
 None
 1.08A 6ak3B-1skyB:
undetectable		 6ak3B-1skyB:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 1sky F1-ATPASE
(Bacillus
sp.
PS3) 		5 / 10 GLY B  77
ASN B 109
ILE B  75
PRO B 233
GLY B  61
 None
 1.12A 6e5zA-1skyB:
undetectable		 6e5zA-1skyB:
19.58