SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sl5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1sl5 MDC-SIGN1B TYPE I
ISOFORM
(Homo
sapiens) 		4 / 8 THR A 261
TYR A 268
ARG A 312
ILE A 376
 None
 0.94A 2xytE-1sl5A:
0.0		 2xytE-1sl5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1sl5 MDC-SIGN1B TYPE I
ISOFORM
(Homo
sapiens) 		4 / 8 THR A 261
TYR A 268
ARG A 312
ILE A 376
 None
 0.92A 2xytH-1sl5A:
undetectable		 2xytH-1sl5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1sl5 MDC-SIGN1B TYPE I
ISOFORM
(Homo
sapiens) 		3 / 3 TRP A 315
VAL A 292
TRP A 277
 None
 0.96A 3zq8C-1sl5A:
undetectable
3zq8D-1sl5A:
undetectable		 3zq8C-1sl5A:
20.45
3zq8D-1sl5A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1sl5 MDC-SIGN1B TYPE I
ISOFORM
(Homo
sapiens) 		4 / 5 TYR A 268
SER A 380
ALA A 381
GLN A 264
 None
 1.28A 5n4iA-1sl5A:
undetectable		 5n4iA-1sl5A:
17.43