SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1slq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 1slq VP4
(Rotavirus
A) 		3 / 3 TYR A 355
ARG A 363
GLN A 360
 None
 0.87A 1tw4A-1slqA:
1.3		 1tw4A-1slqA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1slq VP4
(Rotavirus
A) 		5 / 11 HIS A 315
ILE A 273
THR A 317
ALA A 299
ASN A 300
 None
 1.44A 2gl0B-1slqA:
0.0
2gl0C-1slqA:
undetectable		 2gl0B-1slqA:
18.35
2gl0C-1slqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1slq VP4
(Rotavirus
A) 		5 / 12 ILE A 273
THR A 317
ALA A 299
ASN A 300
HIS A 315
 None
 1.46A 2gl0A-1slqA:
undetectable
2gl0C-1slqA:
undetectable		 2gl0A-1slqA:
18.35
2gl0C-1slqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1slq VP4
(Rotavirus
A) 		5 / 12 HIS A 315
ILE A 273
THR A 317
ALA A 299
ASN A 300
 None
 1.43A 2gl0D-1slqA:
undetectable
2gl0E-1slqA:
undetectable		 2gl0D-1slqA:
18.35
2gl0E-1slqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1slq VP4
(Rotavirus
A) 		5 / 11 HIS A 315
ILE A 273
THR A 317
ALA A 299
ASN A 300
 None
 1.42A 2gl0E-1slqA:
0.0
2gl0F-1slqA:
undetectable		 2gl0E-1slqA:
18.35
2gl0F-1slqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1slq VP4
(Rotavirus
A) 		5 / 11 ILE A 273
THR A 317
ALA A 299
ASN A 300
HIS A 315
 None
 1.45A 2gl0D-1slqA:
0.0
2gl0F-1slqA:
undetectable		 2gl0D-1slqA:
18.35
2gl0F-1slqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1slq VP4
(Rotavirus
A) 		5 / 12 GLY A 382
ASP A 384
ILE A 379
LEU A 450
PRO A 451
 None
 1.05A 3eeyD-1slqA:
undetectable		 3eeyD-1slqA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 1slq VP4
(Rotavirus
A) 		3 / 3 PHE A 326
LYS A 346
SER A 349
 None
 1.28A 3tyeB-1slqA:
undetectable		 3tyeB-1slqA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1slq VP4
(Rotavirus
A) 		3 / 3 VAL A 344
ALA A 453
PHE A 296
 None
 0.90A 4w5nA-1slqA:
undetectable		 4w5nA-1slqA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 1slq VP4
(Rotavirus
A) 		3 / 3 GLU A 463
ARG A 274
TYR A 461
 None
 0.62A 5trqB-1slqA:
0.0		 5trqB-1slqA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1slq VP4
(Rotavirus
A) 		3 / 3 ASP A 478
ARG A 363
ASP A 253
 None
 0.84A 5zvgA-1slqA:
undetectable		 5zvgA-1slqA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1slq VP4
(Rotavirus
A) 		3 / 3 ASP A 478
ARG A 363
ASP A 253
 None
 0.88A 5zvgB-1slqA:
undetectable		 5zvgB-1slqA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1slq VP4
(Rotavirus
A) 		5 / 12 VAL A 353
THR A 316
LEU A 430
PHE A 277
LEU A 450
 None
 1.05A 6a93B-1slqA:
undetectable		 6a93B-1slqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1slq VP4
(Rotavirus
A) 		4 / 7 ASP A 357
ARG A 307
TYR A 305
ASP A 270
 None
 1.35A 6mn5B-1slqA:
undetectable		 6mn5B-1slqA:
16.04