SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JG4_A_SAMA500_1 (PROTEIN-L-ISOASPARTA TE O-METHYLTRANSFERASE)	1sp0	CYTOCHROME C OXIDASE ASSEMBLY PROTEIN CTAG (Sinorhizobium meliloti)	4 / 8	GLY A 61 ARG A 59 LEU A 29 ASP A 57	None	0.79A	1jg4A-1sp0A: undetectable	1jg4A-1sp0A: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_A_TPVA100_2 (HIV-1 PROTEASE)	1sp0	CYTOCHROME C OXIDASE ASSEMBLY PROTEIN CTAG (Sinorhizobium meliloti)	5 / 7	LEU A 108 ASN A 72 ALA A 74 GLY A 44 THR A 107	None	1.44A	3spkB-1sp0A: undetectable	3spkB-1sp0A: 16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X80_A_SALA201_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	1sp0	CYTOCHROME C OXIDASE ASSEMBLY PROTEIN CTAG (Sinorhizobium meliloti)	4 / 5	VAL A 41 PRO A 146 GLY A 44 TYR A 145	None	1.35A	5x80A-1sp0A: undetectable 5x80B-1sp0A: undetectable	5x80A-1sp0A: 21.91 5x80B-1sp0A: 21.91