SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1spb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1480_0
(MJ0495-LIKE PROTEIN)
1spb SUBTILISIN BPN'
PROSEGMENT

(Bacillus
amyloliquefacien
s)
4 / 4 LYS P   9
GLU P  69
ILE P  11
SER P  48
None
1.00A 4ac9C-1spbP:
undetectable
4ac9C-1spbP:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)
1spb SUBTILISIN BPN'
PROSEGMENT

(Bacillus
amyloliquefacien
s)
4 / 4 LYS P   9
GLU P  69
ILE P  11
SER P  48
None
1.01A 4acaC-1spbP:
undetectable
4acaC-1spbP:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)
1spb SUBTILISIN BPN'
PROSEGMENT

(Bacillus
amyloliquefacien
s)
4 / 4 LYS P   9
GLU P  69
ILE P  11
SER P  48
None
0.99A 4acbC-1spbP:
undetectable
4acbC-1spbP:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
1spb SUBTILISIN BPN'
PROSEGMENT

(Bacillus
amyloliquefacien
s)
5 / 7 ILE P  30
LEU P  51
GLU P  58
GLY P  34
GLY P  35
None
1.45A 5a06A-1spbP:
undetectable
5a06A-1spbP:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
1spb SUBTILISIN BPN'
PROSEGMENT

(Bacillus
amyloliquefacien
s)
5 / 7 ILE P  30
LEU P  51
GLU P  58
GLY P  34
GLY P  35
None
1.45A 5a06C-1spbP:
undetectable
5a06C-1spbP:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
1spb SUBTILISIN BPN'
PROSEGMENT

(Bacillus
amyloliquefacien
s)
5 / 7 ILE P  30
LEU P  51
GLU P  58
GLY P  34
GLY P  35
None
1.45A 5a06E-1spbP:
undetectable
5a06E-1spbP:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
1spb SUBTILISIN BPN'
PROSEGMENT

(Bacillus
amyloliquefacien
s)
5 / 7 ILE P  30
LEU P  51
GLU P  58
GLY P  34
GLY P  35
None
1.46A 5a06F-1spbP:
undetectable
5a06F-1spbP:
13.11