SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		5 / 9 LEU A  24
ILE A  25
VAL A  61
GLY A  60
ALA A  51
 None
 1.06A 1e7aA-1sq7A:
undetectable		 1e7aA-1sq7A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		5 / 12 ILE A 243
PHE A 229
ALA A 221
ASN A 245
THR A  37
 None
 0.85A 2rlcA-1sq7A:
0.0		 2rlcA-1sq7A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		4 / 7 VAL A   8
ILE A 243
ALA A 246
GLY A 228
 None
 0.73A 2xrzB-1sq7A:
undetectable		 2xrzB-1sq7A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		4 / 7 GLY A 210
ALA A 181
ALA A 176
VAL A 226
 None
 0.79A 3a2qA-1sq7A:
0.3		 3a2qA-1sq7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		5 / 12 ALA A 181
VAL A 184
GLY A 128
GLU A 165
THR A 172
 None
 1.11A 3c6gB-1sq7A:
0.0		 3c6gB-1sq7A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		5 / 12 ILE A  83
ILE A  46
ILE A  78
ALA A  43
LEU A  21
 None
 1.14A 3uj7B-1sq7A:
undetectable		 3uj7B-1sq7A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		4 / 8 ASP A 242
ILE A 243
PHE A 240
GLY A  10
 None
 0.80A 4ac9C-1sq7A:
3.3		 4ac9C-1sq7A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		4 / 9 ILE A  59
THR A  37
ASN A 245
ILE A 244
 None
 1.05A 5lg3I-1sq7A:
undetectable		 5lg3I-1sq7A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		5 / 11 LEU A  48
ASP A  49
GLY A  87
LEU A  55
VAL A  61
 None
 0.93A 5twjD-1sq7A:
undetectable		 5twjD-1sq7A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		5 / 11 THR A  37
PHE A   6
ALA A 221
THR A 213
ALA A 234
 None
 1.07A 6efnA-1sq7A:
7.3		 6efnA-1sq7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		4 / 6 GLN A 182
GLU A 183
ALA A 181
GLN A 223
 None
 1.33A 6f6jC-1sq7A:
undetectable
6f6jD-1sq7A:
undetectable		 6f6jC-1sq7A:
19.06
6f6jD-1sq7A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		4 / 8 ASP A 106
ILE A 150
ARG A  99
TRP A 191
 None
 1.26A 6hisC-1sq7A:
undetectable
6hisD-1sq7A:
undetectable		 6hisC-1sq7A:
16.07
6hisD-1sq7A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1sq7 TRIOSEPHOSPHATE
ISOMERASE
(Gallus
gallus) 		4 / 8 TRP A 191
ASP A 106
ILE A 150
ARG A  99
 None
 1.26A 6hisA-1sq7A:
undetectable
6hisE-1sq7A:
undetectable		 6hisA-1sq7A:
16.07
6hisE-1sq7A:
16.07