SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sqe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 1sqe HYPOTHETICAL PROTEIN
PG130
(Staphylococcus
aureus) 		4 / 4 SER A 110
ILE A 108
VAL A  67
THR A  71
 None
 0.79A 1u70A-1sqeA:
undetectable		 1u70A-1sqeA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1sqe HYPOTHETICAL PROTEIN
PG130
(Staphylococcus
aureus) 		3 / 3 TRP A  82
TRP A  73
THR A  71
 None
 1.01A 4bboB-1sqeA:
undetectable		 4bboB-1sqeA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 1sqe HYPOTHETICAL PROTEIN
PG130
(Staphylococcus
aureus) 		4 / 7 VAL A 113
ALA A  20
LEU A  24
LEU A  83
 None
 0.82A 4l9iA-1sqeA:
undetectable		 4l9iA-1sqeA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 1sqe HYPOTHETICAL PROTEIN
PG130
(Staphylococcus
aureus) 		4 / 6 THR A  34
ARG A  37
GLN A 104
ILE A 108
 None
 1.41A 6ef6A-1sqeA:
undetectable		 6ef6A-1sqeA:
14.29