SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sr2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1sr2 PUTATIVE SENSOR-LIKE
HISTIDINE KINASE
YOJN
(Escherichia
coli) 		4 / 5 THR A 840
LEU A 844
VAL A 847
LEU A 851
 None
 0.67A 1fbmE-1sr2A:
undetectable		 1fbmE-1sr2A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1sr2 PUTATIVE SENSOR-LIKE
HISTIDINE KINASE
YOJN
(Escherichia
coli) 		3 / 3 THR A 840
LEU A 844
VAL A 847
 None
 0.60A 1mz9E-1sr2A:
undetectable		 1mz9E-1sr2A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 1sr2 PUTATIVE SENSOR-LIKE
HISTIDINE KINASE
YOJN
(Escherichia
coli) 		3 / 3 LYS A 870
ARG A 868
HIS A 865
 None
 1.26A 4zbrA-1sr2A:
2.6		 4zbrA-1sr2A:
11.84