SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sra'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1sra SPARC
(Homo
sapiens) 		4 / 8 LEU A 258
ALA A 265
ILE A 264
GLY A 271
 None
 0.68A 1sv9A-1sraA:
undetectable		 1sv9A-1sraA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1sra SPARC
(Homo
sapiens) 		4 / 8 VAL A 157
TRP A 153
LEU A 221
LEU A 238
 None
 1.02A 4jtrA-1sraA:
undetectable		 4jtrA-1sraA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 1sra SPARC
(Homo
sapiens) 		3 / 3 VAL A 159
TYR A 162
GLU A 190
 None
 0.99A 5zmqD-1sraA:
undetectable
5zmqE-1sraA:
undetectable		 5zmqD-1sraA:
21.58
5zmqE-1sraA:
18.38