SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ss4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 LEU A 110
THR A 111
ILE A 141
ILE A 139
GLY A 138
 None
 0.99A 1qknA-1ss4A:
undetectable		 1qknA-1ss4A:
19.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 5 TRP A  43
VAL A  47
THR A  48
GLN A  53
ILE A  57
 None
ACT  A 411 (-4.1A)
ACT  A 411 (-4.6A)
ACT  A 411 ( 4.4A)
None
 0.00A 1ss4A-1ss4A:
27.0		 1ss4A-1ss4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 7 PHE A  26
VAL A  16
VAL A  12
ILE A  69
 None
 0.98A 1t87B-1ss4A:
undetectable		 1t87B-1ss4A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A 142
LEU A 143
LEU A 130
ILE A 103
LEU A 117
 None
 1.11A 2f8dA-1ss4A:
undetectable		 2f8dA-1ss4A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A 142
LEU A 143
LEU A 130
ILE A 103
LEU A 117
 None
 1.11A 2f8dB-1ss4A:
undetectable		 2f8dB-1ss4A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 8 PHE A  26
VAL A  16
VAL A  12
ILE A  69
 None
 0.94A 2qbmA-1ss4A:
undetectable		 2qbmA-1ss4A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		3 / 3 ARG A 129
LEU A 147
THR A  99
 None
 0.84A 3oxcA-1ss4A:
undetectable		 3oxcA-1ss4A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ss4 GLYOXALASE FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 8 PHE A  26
VAL A  16
VAL A  12
ILE A  69
 None
 0.96A 4l4cB-1ss4A:
undetectable		 4l4cB-1ss4A:
16.26