SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ssq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_1
(HISTONE
METHYLTRANSFERASE
DOT1L)		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 4 THR A 113
GLN A 129
GLU A 162
ASP A 187
 None
 1.49A 1nw3A-1ssqA:
0.0		 1nw3A-1ssqA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 9 ASP A  80
ILE A 150
GLY A 149
VAL A 192
GLY A 195
 None
 1.19A 4acaB-1ssqA:
undetectable
4acaC-1ssqA:
undetectable		 4acaB-1ssqA:
19.96
4acaC-1ssqA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 4 ALA A  90
VAL A  91
ASP A  88
LEU A 101
 CYS  A2000 (-3.5A)
None
CYS  A2000 (-3.1A)
None
 0.95A 4e7gA-1ssqA:
0.0		 4e7gA-1ssqA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 9 ILE A 112
THR A 113
GLN A 129
LEU A 128
LEU A 124
 None
 1.21A 4g1bC-1ssqA:
undetectable		 4g1bC-1ssqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		4 / 8 ASN A  36
GLN A 108
GLN A  68
ILE A  73
 None
 1.10A 4iilA-1ssqA:
undetectable		 4iilA-1ssqA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 11 PHE A 104
ILE A  74
TYR A  67
ILE A  63
ILE A 112
 None
 1.21A 5hw8E-1ssqA:
undetectable		 5hw8E-1ssqA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 MET A  54
GLN A 131
LEU A  59
ILE A  62
TYR A 115
 None
 1.34A 5vlmB-1ssqA:
1.7		 5vlmB-1ssqA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 1ssq SERINE
ACETYLTRANSFERASE
(Haemophilus
influenzae) 		5 / 12 VAL A 160
ILE A 166
GLY A 147
LEU A 178
ILE A 140
 None
 0.95A 6dh6B-1ssqA:
undetectable		 6dh6B-1ssqA:
18.48