SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1su1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		4 / 8 ILE A  34
PHE A  85
ARG A  59
LEU A  39
 None
 0.93A 2eikN-1su1A:
undetectable
2eikW-1su1A:
undetectable		 2eikN-1su1A:
19.04
2eikW-1su1A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		4 / 8 HIS A  11
ASP A  37
HIS A 129
ASP A   9
 ZN  A 302 ( 3.4A)
ZN  A 301 (-2.9A)
ZN  A 302 ( 3.4A)
ZN  A 302 ( 2.9A)
 1.13A 2xadB-1su1A:
undetectable		 2xadB-1su1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		4 / 8 HIS A  11
ASP A  37
HIS A 129
ASP A   9
 ZN  A 302 ( 3.4A)
ZN  A 301 (-2.9A)
ZN  A 302 ( 3.4A)
ZN  A 302 ( 2.9A)
 1.11A 2xadC-1su1A:
undetectable		 2xadC-1su1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		4 / 8 HIS A  11
ASP A  37
HIS A 129
ASP A   9
 ZN  A 302 ( 3.4A)
ZN  A 301 (-2.9A)
ZN  A 302 ( 3.4A)
ZN  A 302 ( 2.9A)
 1.12A 2xadD-1su1A:
undetectable		 2xadD-1su1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		3 / 3 HIS A 105
HIS A 127
HIS A 107
 ZN  A 301 (-3.4A)
ZN  A 301 ( 3.3A)
None
 0.79A 3mihA-1su1A:
undetectable		 3mihA-1su1A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		3 / 3 HIS A 107
HIS A 105
HIS A 127
 None
ZN  A 301 (-3.4A)
ZN  A 301 ( 3.3A)
 0.78A 3mihA-1su1A:
undetectable		 3mihA-1su1A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		3 / 3 HIS A 127
HIS A 107
HIS A 105
 ZN  A 301 ( 3.3A)
None
ZN  A 301 (-3.4A)
 0.35A 3mihA-1su1A:
undetectable		 3mihA-1su1A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 12 ILE A  34
VAL A  56
VAL A  57
LEU A  32
PHE A  85
 None
 0.85A 5bykA-1su1A:
undetectable		 5bykA-1su1A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		4 / 6 ALA A  16
THR A  17
VAL A  20
VAL A  38
 None
 1.00A 5eclA-1su1A:
undetectable		 5eclA-1su1A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 12 ILE A  34
GLY A  36
ALA A   7
LEU A  32
VAL A  20
 None
 1.22A 5hw4A-1su1A:
0.8		 5hw4A-1su1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 11 ILE A  34
GLY A  36
ALA A   7
LEU A  32
VAL A  20
 None
 1.21A 5hw4B-1su1A:
undetectable		 5hw4B-1su1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 12 ILE A  34
GLY A  36
ALA A   7
LEU A  32
VAL A  20
 None
 1.17A 5hw4C-1su1A:
undetectable		 5hw4C-1su1A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 12 GLN A 179
ALA A 178
SER A 167
ILE A 182
PHE A   6
 None
 1.48A 5vlmA-1su1A:
undetectable		 5vlmA-1su1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 12 GLY A 106
HIS A  11
PRO A 111
THR A 104
PHE A 102
 None
ZN  A 302 ( 3.4A)
None
None
None
 1.21A 5x6yA-1su1A:
undetectable		 5x6yA-1su1A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 12 ILE A  34
VAL A  56
VAL A  57
LEU A  32
PHE A  85
 None
 0.99A 6b52A-1su1A:
undetectable		 6b52A-1su1A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 1su1 HYPOTHETICAL PROTEIN
YFCE
(Escherichia
coli) 		5 / 12 HIS A  11
GLY A  42
ILE A  34
LEU A  35
GLY A  72
 ZN  A 302 ( 3.4A)
None
None
None
None
 1.03A 6c2mA-1su1A:
undetectable		 6c2mA-1su1A:
15.38