SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1suj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		3 / 3 ARG A  24
TYR A   8
LYS A   6
 None
 0.85A 1uujB-1sujA:
undetectable		 1uujB-1sujA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		5 / 12 GLN A 234
LEU A 286
LEU A 126
THR A 236
LEU A 290
 None
 1.13A 3fsuA-1sujA:
undetectable		 3fsuA-1sujA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		3 / 3 SER A 338
SER A 337
HIS A 323
 None
 0.85A 3mzeA-1sujA:
undetectable		 3mzeA-1sujA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		4 / 5 ILE A 303
THR A 301
THR A 300
SER A 317
 None
 1.09A 3snfA-1sujA:
undetectable		 3snfA-1sujA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		5 / 12 LEU A 105
LEU A  21
VAL A  40
GLY A  38
LEU A  94
 None
 1.05A 4otyB-1sujA:
undetectable		 4otyB-1sujA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		5 / 12 LEU A 105
LEU A  21
VAL A  40
GLY A  38
LEU A  94
 None
 1.05A 4rrwD-1sujA:
0.0		 4rrwD-1sujA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		5 / 12 LEU A 105
LEU A  21
VAL A  40
GLY A  38
LEU A  94
 None
 1.05A 4rrzD-1sujA:
0.0		 4rrzD-1sujA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		4 / 6 PHE A 114
PRO A  35
VAL A  36
THR A  95
 None
 0.79A 5t7bA-1sujA:
undetectable		 5t7bA-1sujA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		4 / 6 LYS A 144
LEU A 163
PHE A 369
LEU A  21
 None
 1.22A 5x19P-1sujA:
undetectable		 5x19P-1sujA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 1suj CONE ARRESTIN
(Ambystoma
tigrinum) 		4 / 5 THR A 295
THR A 236
GLN A 234
ASP A 244
 None
 1.27A 6ecxA-1sujA:
undetectable		 6ecxA-1sujA:
22.00