SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sv0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 1sv0 MODULATOR OF THE
ACTIVITY OF ETS
CG15085-PA
(Drosophila
melanogaster) 		4 / 5 LEU C 131
GLU C 126
ALA C 120
LEU C 116
 None
 1.16A 1eta2-1sv0C:
undetectable		 1eta2-1sv0C:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 1sv0 ETS DNA-BINDING
PROTEIN POKKURI
(Drosophila
melanogaster) 		4 / 5 LEU A 113
ASP A  50
LEU A  63
HIS A 107
 None
 1.30A 2jfaA-1sv0A:
undetectable		 2jfaA-1sv0A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 1sv0 MODULATOR OF THE
ACTIVITY OF ETS
CG15085-PA
(Drosophila
melanogaster) 		4 / 6 LEU C 151
TRP C 115
MET C 119
LEU C 131
 None
 1.44A 2oz7A-1sv0C:
undetectable		 2oz7A-1sv0C:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 1sv0 ETS DNA-BINDING
PROTEIN POKKURI
(Drosophila
melanogaster) 		3 / 3 PHE A  62
CYH A  66
PHE A  70
 None
 1.03A 3cr5X-1sv0A:
undetectable		 3cr5X-1sv0A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 1sv0 MODULATOR OF THE
ACTIVITY OF ETS
CG15085-PA
(Drosophila
melanogaster) 		5 / 12 GLY C  96
GLY C  99
ASP C  98
TRP C 107
LEU C 102
 None
 1.19A 5bw4A-1sv0C:
undetectable		 5bw4A-1sv0C:
16.21