SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sva'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		4 / 8 GLY 1 156
GLY 1 155
TYR 1 260
VAL 1  47
 None
 0.90A 1dbbH-1sva1:
undetectable
1dbbL-1sva1:
undetectable		 1dbbH-1sva1:
18.48
1dbbL-1sva1:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		5 / 12 ILE 1 288
GLY 1 156
ALA 1 112
ASP 1 198
LEU 1 197
 None
 1.24A 1i9gA-1sva1:
undetectable		 1i9gA-1sva1:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		4 / 8 LEU 1 197
ALA 1 153
GLY 1 222
LEU 1 161
 None
 0.75A 2o4nB-1sva1:
undetectable		 2o4nB-1sva1:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		4 / 4 PHE 1 149
TYR 1 220
VAL 1 122
LEU 1 282
 None
 1.23A 3keeD-1sva1:
0.0		 3keeD-1sva1:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MYU_A_VIBA500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		5 / 10 ASP 1 265
HIS 1 150
ASN 1  57
ILE 1 266
GLY 1 268
 None
 1.31A 3myuA-1sva1:
undetectable		 3myuA-1sva1:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		5 / 7 THR 1 218
PRO 1 210
ASN 1 215
GLY 1 222
THR 1 223
 None
 1.37A 3tajA-1sva1:
undetectable		 3tajA-1sva1:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		3 / 3 TRP 1 110
MET 1 109
ASN 1  99
 None
 1.37A 5uc1B-1sva1:
undetectable		 5uc1B-1sva1:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		3 / 3 TRP 1 110
MET 1 109
ASN 1  99
 None
 1.31A 5uc1A-1sva1:
undetectable		 5uc1A-1sva1:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1sva SIMIAN VIRUS 40
(Macaca
mulatta
polyomavirus
1) 		4 / 7 ALA 1 263
ILE 1 288
VAL 1 261
PRO 1 252
 None
 0.90A 6cduF-1sva1:
undetectable
6cduJ-1sva1:
undetectable		 6cduF-1sva1:
21.35
6cduJ-1sva1:
21.35