SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1svi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_D_VDYD1001_3 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	1svi	GTP-BINDING PROTEIN YSXC (Bacillus subtilis)	3 / 3	THR A 162 LEU A 163 LEU A 130	None	0.46A	1mz9C-1sviA: undetectable	1mz9C-1sviA: 12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QHY_A_CLMA999_0 (CHLORAMPHENICOL PHOSPHOTRANSFERASE)	1svi	GTP-BINDING PROTEIN YSXC (Bacillus subtilis)	5 / 12	ILE A 135 ILE A 100 ILE A 96 VAL A 74 LEU A 62	None	1.01A	1qhyA-1sviA: 4.4	1qhyA-1sviA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DTT_C_H4BC1002_1 (HYPOTHETICAL PROTEIN PH0634)	1svi	GTP-BINDING PROTEIN YSXC (Bacillus subtilis)	4 / 6	TYR A 132 PHE A 129 THR A 101 GLU A 97	None	1.40A	2dttB-1sviA: undetectable 2dttC-1sviA: 0.0	2dttB-1sviA: 20.20 2dttC-1sviA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_B_VDYB6178_1 (VITAMIN D HYDROXYLASE)	1svi	GTP-BINDING PROTEIN YSXC (Bacillus subtilis)	5 / 12	PRO A 24 LYS A 190 ASN A 194 ILE A 138 LEU A 43	None	1.33A	3a51B-1sviA: undetectable	3a51B-1sviA: 17.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MZ9_D_VDYD1001_3","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","1svi","GTP-BINDING PROTEIN YSXC","Bacillus subtilis",3,"THR A 162;LEU A 163;LEU A 130","None","0.46A","1mz9C-1sviA:undetectable","1mz9C-1sviA:12.90"],["1QHY_A_CLMA999_0","CHLORAMPHENICOL PHOSPHOTRANSFERASE","1svi","GTP-BINDING PROTEIN YSXC","Bacillus subtilis",5,"ILE A 135;ILE A 100;ILE A  96;VAL A  74;LEU A  62","None","1.01A","1qhyA-1sviA:4.4","1qhyA-1sviA:23.38"],["2DTT_C_H4BC1002_1","HYPOTHETICAL PROTEIN PH0634;HYPOTHETICAL PROTEIN PH0634","1svi","GTP-BINDING PROTEIN YSXC","Bacillus subtilis",4,"TYR A 132;PHE A 129;THR A 101;GLU A  97","None","1.40A","2dttB-1sviA:undetectable;2dttC-1sviA:0.0","2dttB-1sviA:20.20;2dttC-1sviA:20.20"],["3A51_B_VDYB6178_1","VITAMIN D HYDROXYLASE","1svi","GTP-BINDING PROTEIN YSXC","Bacillus subtilis",5,"PRO A  24;LYS A 190;ASN A 194;ILE A 138;LEU A  43","None","1.33A","3a51B-1sviA:undetectable","3a51B-1sviA:17.41"]]