SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1svr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.88A 2eikC-1svrA:
undetectable
2eikJ-1svrA:
undetectable		 2eikC-1svrA:
17.37
2eikJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 8 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.86A 2eikP-1svrA:
undetectable
2eikW-1svrA:
undetectable		 2eikP-1svrA:
17.37
2eikW-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 8 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.88A 2eilC-1svrA:
undetectable
2eilJ-1svrA:
undetectable		 2eilC-1svrA:
17.37
2eilJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 8 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.84A 2eilP-1svrA:
undetectable
2eilW-1svrA:
undetectable		 2eilP-1svrA:
17.37
2eilW-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.89A 3ablP-1svrA:
undetectable
3ablW-1svrA:
undetectable		 3ablP-1svrA:
17.37
3ablW-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.85A 3ag2P-1svrA:
undetectable
3ag2W-1svrA:
undetectable		 3ag2P-1svrA:
17.37
3ag2W-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 8 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.84A 3ag4C-1svrA:
undetectable
3ag4J-1svrA:
undetectable		 3ag4C-1svrA:
17.37
3ag4J-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.83A 3ag4P-1svrA:
undetectable
3ag4W-1svrA:
undetectable		 3ag4P-1svrA:
17.37
3ag4W-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 8 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.87A 3asoC-1svrA:
undetectable
3asoJ-1svrA:
undetectable		 3asoC-1svrA:
17.37
3asoJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.73A 3x2qC-1svrA:
undetectable
3x2qJ-1svrA:
undetectable		 3x2qC-1svrA:
17.37
3x2qJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.73A 3x2qP-1svrA:
undetectable
3x2qW-1svrA:
undetectable		 3x2qP-1svrA:
17.37
3x2qW-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 8 ASP A 222
ILE A 221
ASP A 193
ILE A 198
 None
 0.86A 4kttD-1svrA:
undetectable		 4kttD-1svrA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 8 ALA A 220
ILE A 221
ALA A 175
LEU A 191
 None
 0.67A 4v1fA-1svrA:
undetectable
4v1fB-1svrA:
undetectable		 4v1fA-1svrA:
19.30
4v1fB-1svrA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.77A 5b1aC-1svrA:
undetectable
5b1aJ-1svrA:
undetectable		 5b1aC-1svrA:
17.37
5b1aJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.75A 5b1aP-1svrA:
undetectable
5b1aW-1svrA:
undetectable		 5b1aP-1svrA:
17.37
5b1aW-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.92A 5b1bC-1svrA:
undetectable
5b1bJ-1svrA:
undetectable		 5b1bC-1svrA:
17.37
5b1bJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.78A 5b3sC-1svrA:
undetectable
5b3sJ-1svrA:
undetectable		 5b3sC-1svrA:
17.37
5b3sJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.73A 5b3sP-1svrA:
undetectable		 5b3sP-1svrA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.87A 5iy5C-1svrA:
undetectable
5iy5J-1svrA:
undetectable		 5iy5C-1svrA:
17.37
5iy5J-1svrA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.79A 5z84C-1svrA:
undetectable
5z84J-1svrA:
undetectable		 5z84C-1svrA:
17.37
5z84J-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.79A 5z84P-1svrA:
undetectable
5z84W-1svrA:
undetectable		 5z84P-1svrA:
17.37
5z84W-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.76A 5z85C-1svrA:
undetectable
5z85J-1svrA:
undetectable		 5z85C-1svrA:
17.37
5z85J-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.78A 5z85P-1svrA:
undetectable
5z85W-1svrA:
undetectable		 5z85P-1svrA:
17.37
5z85W-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.77A 5z86C-1svrA:
undetectable
5z86J-1svrA:
undetectable		 5z86C-1svrA:
17.37
5z86J-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.77A 5z86P-1svrA:
undetectable
5z86W-1svrA:
undetectable		 5z86P-1svrA:
17.37
5z86W-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.77A 5zcoC-1svrA:
undetectable
5zcoJ-1svrA:
undetectable		 5zcoC-1svrA:
17.37
5zcoJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.81A 5zcoP-1svrA:
undetectable
5zcoW-1svrA:
undetectable		 5zcoP-1svrA:
17.37
5zcoW-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.77A 5zcpC-1svrA:
undetectable
5zcpJ-1svrA:
undetectable		 5zcpC-1svrA:
17.37
5zcpJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 6 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.80A 5zcpP-1svrA:
undetectable
5zcpW-1svrA:
undetectable		 5zcpP-1svrA:
17.37
5zcpW-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.85A 5zcqC-1svrA:
undetectable
5zcqJ-1svrA:
undetectable		 5zcqC-1svrA:
17.37
5zcqJ-1svrA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1svr SEVERIN
(Dictyostelium
discoideum) 		4 / 7 GLN A 200
PHE A 201
PHE A 245
LEU A 249
 None
 0.72A 5zcqP-1svrA:
undetectable
5zcqW-1svrA:
undetectable		 5zcqP-1svrA:
17.37
5zcqW-1svrA:
26.15