SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sxe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1sxe TRANSCRIPTIONAL
REGULATOR ERG
(Homo
sapiens) 		3 / 3 TRP A 142
GLU A 149
TYR A 150
 None
 1.24A 2a3aA-1sxeA:
undetectable		 2a3aA-1sxeA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1sxe TRANSCRIPTIONAL
REGULATOR ERG
(Homo
sapiens) 		4 / 5 MET A 171
PRO A 131
VAL A 139
TRP A 134
 None
 1.43A 2pnjA-1sxeA:
undetectable		 2pnjA-1sxeA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1sxe TRANSCRIPTIONAL
REGULATOR ERG
(Homo
sapiens) 		4 / 8 ALA A 146
GLY A 151
LEU A 152
LEU A 188
 None
 0.80A 4po0A-1sxeA:
undetectable		 4po0A-1sxeA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1sxe TRANSCRIPTIONAL
REGULATOR ERG
(Homo
sapiens) 		4 / 9 ALA A 146
GLU A 149
LEU A 192
LEU A 195
 None
 0.87A 4xtaA-1sxeA:
undetectable		 4xtaA-1sxeA:
17.78