SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.56A 1rjoA-1sxzA:
undetectable
1rjoA-1sxzA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.60A 1rkyA-1sxzA:
undetectable
1rkyA-1sxzA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 1v54A-1sxzA:
undetectable
1v54A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 1v54N-1sxzA:
undetectable
1v54N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.63A 1v55A-1sxzA:
undetectable
1v55A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.64A 1v55N-1sxzA:
undetectable
1v55N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.57A 1w2zA-1sxzA:
undetectable
1w2zA-1sxzA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.54A 1w2zB-1sxzA:
undetectable
1w2zB-1sxzA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.54A 1w2zC-1sxzA:
undetectable
1w2zC-1sxzA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.55A 1w2zD-1sxzA:
undetectable
1w2zD-1sxzA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
5 / 12 ILE A 110
HIS A  69
HIS A  61
GLY A  80
GLY A  71
None
ZN  A 153 ( 3.2A)
ZN  A 153 ( 3.1A)
None
None
1.12A 1zz1C-1sxzA:
undetectable
1zz1C-1sxzA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 2dyrA-1sxzA:
undetectable
2dyrA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 2dyrN-1sxzA:
undetectable
2dyrN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.56A 2dysA-1sxzA:
undetectable
2dysA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.53A 2dysN-1sxzA:
undetectable
2dysN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 2eijA-1sxzA:
undetectable
2eijA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 2eijN-1sxzA:
undetectable
2eijN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.58A 2eikA-1sxzA:
undetectable
2eikA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 2eikN-1sxzA:
undetectable
2eikN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.57A 2eilA-1sxzA:
undetectable
2eilA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 2eilN-1sxzA:
undetectable
2eilN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.66A 2eimA-1sxzA:
undetectable
2eimA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 2eimN-1sxzA:
undetectable
2eimN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.48A 2einA-1sxzA:
undetectable
2einA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 2einN-1sxzA:
undetectable
2einN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.49A 2oqeA-1sxzA:
undetectable
2oqeA-1sxzA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.48A 2oqeB-1sxzA:
undetectable
2oqeB-1sxzA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.50A 2oqeC-1sxzA:
undetectable
2oqeC-1sxzA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.49A 2oqeD-1sxzA:
undetectable
2oqeD-1sxzA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.49A 2oqeF-1sxzA:
2.1
2oqeF-1sxzA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.60A 2w0qA-1sxzA:
undetectable
2w0qA-1sxzA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.54A 2w0qB-1sxzA:
undetectable
2w0qB-1sxzA:
12.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
4 / 4 HIS A  44
HIS A  46
HIS A  61
HIS A 118
CU  A 152 ( 3.1A)
CU  A 152 (-3.4A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.2A)
0.27A 2wkoA-1sxzA:
31.3
2wkoA-1sxzA:
81.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
5 / 5 HIS A  44
HIS A  46
HIS A  61
VAL A 116
HIS A 118
CU  A 152 ( 3.1A)
CU  A 152 (-3.4A)
ZN  A 153 ( 3.1A)
None
CU  A 152 (-3.2A)
0.28A 2wkoF-1sxzA:
31.2
2wkoF-1sxzA:
81.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 2y69A-1sxzA:
undetectable
2y69A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.63A 2y69N-1sxzA:
undetectable
2y69N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 2zxwA-1sxzA:
undetectable
2zxwA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 2zxwN-1sxzA:
undetectable
2zxwN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 3abkA-1sxzA:
undetectable
3abkA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 3abkN-1sxzA:
undetectable
3abkN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.56A 3ablA-1sxzA:
undetectable
3ablA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.54A 3ablN-1sxzA:
undetectable
3ablN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 3abmA-1sxzA:
undetectable
3abmA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.58A 3abmN-1sxzA:
undetectable
3abmN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.66A 3ag1A-1sxzA:
undetectable
3ag1A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.67A 3ag1N-1sxzA:
undetectable
3ag1N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 3ag2A-1sxzA:
undetectable
3ag2A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 3ag2N-1sxzA:
undetectable
3ag2N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 3ag3A-1sxzA:
undetectable
3ag3A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 3ag3N-1sxzA:
undetectable
3ag3N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.74A 3ag4N-1sxzA:
undetectable
3ag4N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 3asnA-1sxzA:
undetectable
3asnA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 3asnN-1sxzA:
undetectable
3asnN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 3asoA-1sxzA:
undetectable
3asoA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.58A 3asoN-1sxzA:
undetectable
3asoN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 3bvdA-1sxzA:
undetectable
3bvdA-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.68A 3dtuA-1sxzA:
undetectable
3dtuA-1sxzA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.67A 3dtuC-1sxzA:
undetectable
3dtuC-1sxzA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.47A 3hiiA-1sxzA:
2.3
3hiiA-1sxzA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
HIS A  46
HIS A  44
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
CU  A 152 ( 3.1A)
0.49A 3hiiB-1sxzA:
2.0
3hiiB-1sxzA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
4 / 8 VAL A  79
VAL A  27
TYR A 108
ILE A 110
None
0.95A 3remA-1sxzA:
undetectable
3remA-1sxzA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
4 / 8 VAL A  79
VAL A  27
TYR A 108
ILE A 110
None
0.96A 3remB-1sxzA:
undetectable
3remB-1sxzA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 3s33A-1sxzA:
undetectable
3s33A-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 3s38A-1sxzA:
undetectable
3s38A-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.57A 3s39A-1sxzA:
undetectable
3s39A-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.63A 3s3aA-1sxzA:
undetectable
3s3aA-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 3s3bA-1sxzA:
undetectable
3s3bA-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 3s3cA-1sxzA:
undetectable
3s3cA-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.54A 3s3dA-1sxzA:
undetectable
3s3dA-1sxzA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.57A 3wg7A-1sxzA:
undetectable
3wg7A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 3wg7N-1sxzA:
undetectable
3wg7N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 3x2qA-1sxzA:
undetectable
3x2qA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.65A 3x2qN-1sxzA:
undetectable
3x2qN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
5 / 12 ALA A  93
SER A  32
VAL A  95
PHE A  43
HIS A 118
None
None
None
None
CU  A 152 (-3.2A)
1.25A 4c49A-1sxzA:
undetectable
4c49A-1sxzA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
4 / 7 GLY A 145
VAL A 146
PHE A  20
ILE A 110
None
0.92A 4fglC-1sxzA:
undetectable
4fglC-1sxzA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.58A 5b1aA-1sxzA:
undetectable
5b1aA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 5b1aN-1sxzA:
undetectable
5b1aN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 5b1bA-1sxzA:
undetectable
5b1bA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 5b1bN-1sxzA:
undetectable
5b1bN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 5b3sA-1sxzA:
undetectable
5b3sA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 5b3sN-1sxzA:
undetectable
5b3sN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
5 / 12 ALA A 138
GLY A  83
GLY A 125
ASP A  81
LEU A  82
None
None
None
ZN  A 153 ( 2.2A)
None
1.04A 5c0oE-1sxzA:
undetectable
5c0oE-1sxzA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 5iy5A-1sxzA:
undetectable
5iy5A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 5iy5N-1sxzA:
undetectable
5iy5N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  61
ASP A  81
HIS A  69
ZN  A 153 ( 3.1A)
ZN  A 153 ( 2.2A)
ZN  A 153 ( 3.2A)
0.84A 5n1tW-1sxzA:
2.6
5n1tW-1sxzA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.66A 5w97a-1sxzA:
undetectable
5w97a-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.62A 5waua-1sxzA:
undetectable
5waua-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.63A 5x19A-1sxzA:
undetectable
5x19A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.64A 5x19N-1sxzA:
undetectable
5x19N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.64A 5x1bA-1sxzA:
undetectable
5x1bA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.64A 5x1bN-1sxzA:
undetectable
5x1bN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.66A 5x1fA-1sxzA:
undetectable
5x1fA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.65A 5x1fN-1sxzA:
undetectable
5x1fN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.57A 5xdqA-1sxzA:
undetectable
5xdqA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 5xdqN-1sxzA:
undetectable
5xdqN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 5xdxA-1sxzA:
undetectable
5xdxA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.63A 5xdxN-1sxzA:
undetectable
5xdxN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.56A 5z84A-1sxzA:
undetectable
5z84A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.60A 5z84N-1sxzA:
undetectable
5z84N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 5z85A-1sxzA:
undetectable
5z85A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.58A 5z85N-1sxzA:
undetectable
5z85N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.55A 5z86A-1sxzA:
undetectable
5z86A-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 5z86N-1sxzA:
undetectable
5z86N-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.58A 5zcoA-1sxzA:
undetectable
5zcoA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.57A 5zcoN-1sxzA:
undetectable
5zcoN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.56A 5zcpA-1sxzA:
undetectable
5zcpA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 5zcpN-1sxzA:
undetectable
5zcpN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.55A 5zcqA-1sxzA:
undetectable
5zcqA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.57A 5zcqN-1sxzA:
undetectable
5zcqN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.63A 6hu9a-1sxzA:
undetectable
6hu9a-1sxzA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.61A 6hu9m-1sxzA:
undetectable
6hu9m-1sxzA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.58A 6nknA-1sxzA:
undetectable
6nknA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.55A 6nknN-1sxzA:
undetectable
6nknN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.64A 6nmfA-1sxzA:
undetectable
6nmfA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.67A 6nmfN-1sxzA:
undetectable
6nmfN-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.63A 6nmpA-1sxzA:
undetectable
6nmpA-1sxzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1sxz PROTEIN (CU-ZN
SUPEROXIDE
DISMUTASE)

(Bos
taurus)
3 / 3 HIS A  44
HIS A  61
HIS A  46
CU  A 152 ( 3.1A)
ZN  A 153 ( 3.1A)
CU  A 152 (-3.4A)
0.59A 6nmpN-1sxzA:
undetectable
6nmpN-1sxzA:
13.23