SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1sy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 11 GLY A 656
THR A 655
GLU A 657
LEU A 632
GLY A 625
 None
 1.00A 1i7qA-1sy7A:
undetectable		 1i7qA-1sy7A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.92A 1rxcB-1sy7A:
undetectable		 1rxcB-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.95A 1rxcC-1sy7A:
undetectable		 1rxcC-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.92A 1rxcD-1sy7A:
undetectable		 1rxcD-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.89A 1rxcE-1sy7A:
undetectable		 1rxcE-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.93A 1rxcF-1sy7A:
undetectable		 1rxcF-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.90A 1rxcI-1sy7A:
undetectable		 1rxcI-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.90A 1rxcK-1sy7A:
undetectable		 1rxcK-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.90A 1rxcL-1sy7A:
undetectable		 1rxcL-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 8 ALA A 619
ASP A 618
ILE A 578
ILE A 588
PRO A 623
 None
 1.21A 1sh9A-1sy7A:
undetectable		 1sh9A-1sy7A:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 TRP A 268
ASP A 141
THR A 142
HIS A 648
 None
 1.49A 1v54A-1sy7A:
undetectable
1v54C-1sy7A:
undetectable		 1v54A-1sy7A:
20.82
1v54C-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 LEU A 230
ASP A 141
THR A 142
HIS A 648
 None
 1.20A 1v55C-1sy7A:
0.7
1v55N-1sy7A:
0.0
1v55P-1sy7A:
0.6		 1v55C-1sy7A:
15.64
1v55N-1sy7A:
20.82
1v55P-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 PHE A 203
ARG A 501
ASN A 209
 None
 0.89A 1xzxX-1sy7A:
undetectable		 1xzxX-1sy7A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 9 GLY A 729
THR A 687
VAL A 671
ILE A 666
VAL A 662
 None
 1.32A 2nnhB-1sy7A:
undetectable		 2nnhB-1sy7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 MET A 502
GLU A 489
ASP A 145
 None
 1.11A 3a25A-1sy7A:
undetectable		 3a25A-1sy7A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 TRP A 268
ASP A 141
THR A 142
HIS A 648
 None
 1.50A 3ag4N-1sy7A:
undetectable
3ag4P-1sy7A:
undetectable		 3ag4N-1sy7A:
20.82
3ag4P-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 12 VAL A 146
PHE A 486
GLU A 489
ALA A 213
PHE A 217
 None
 1.33A 3apxA-1sy7A:
2.5		 3apxA-1sy7A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 PRO A 669
LEU A 668
ARG A 643
 None
 0.87A 3aqiA-1sy7A:
2.8		 3aqiA-1sy7A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ASP A 141
THR A 142
HIS A 648
LEU A 230
 None
 1.22A 3asoA-1sy7A:
0.0
3asoC-1sy7A:
0.6
3asoP-1sy7A:
0.6		 3asoA-1sy7A:
20.82
3asoC-1sy7A:
15.64
3asoP-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 ARG A 725
VAL A 659
THR A 687
 None
 0.84A 3cyxA-1sy7A:
0.0		 3cyxA-1sy7A:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 12 ASP A  71
ARG A  75
ARG A  77
GLU A  76
ALA A  52
 None
 1.49A 3k37B-1sy7A:
undetectable		 3k37B-1sy7A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 9 PHE A 300
VAL A 104
ILE A 302
THR A 112
ALA A 114
 None
 1.21A 3mdtA-1sy7A:
undetectable		 3mdtA-1sy7A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 12 PHE A 149
GLY A 164
ALA A  98
GLY A  97
MET A 337
 None
HDD  A1880 ( 3.9A)
None
None
None
 0.95A 3v3oA-1sy7A:
undetectable		 3v3oA-1sy7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 12 PHE A 149
GLY A 164
ALA A  98
GLY A  97
MET A 337
 None
HDD  A1880 ( 3.9A)
None
None
None
 1.10A 3v3oB-1sy7A:
undetectable		 3v3oB-1sy7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 PRO A 669
LEU A 668
ILE A 666
ARG A 643
 None
 1.20A 3w1wA-1sy7A:
undetectable		 3w1wA-1sy7A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 LEU A 230
ASP A 141
THR A 142
HIS A 648
 None
 1.11A 3wg7C-1sy7A:
0.6
3wg7N-1sy7A:
undetectable
3wg7P-1sy7A:
0.6		 3wg7C-1sy7A:
15.64
3wg7N-1sy7A:
20.82
3wg7P-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 6 ILE A 396
PHE A 355
TYR A 154
VAL A 116
 None
HEM  A1883 ( 4.4A)
None
None
 1.16A 4a97I-1sy7A:
undetectable		 4a97I-1sy7A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.91A 4e1vA-1sy7A:
undetectable		 4e1vA-1sy7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.93A 4e1vB-1sy7A:
undetectable		 4e1vB-1sy7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.93A 4e1vC-1sy7A:
undetectable		 4e1vC-1sy7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.96A 4e1vD-1sy7A:
undetectable		 4e1vD-1sy7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.91A 4e1vE-1sy7A:
undetectable		 4e1vE-1sy7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.96A 4e1vG-1sy7A:
undetectable		 4e1vG-1sy7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ARG A 224
MET A 474
ILE A 323
PRO A 168
 None
 0.92A 4e1vH-1sy7A:
undetectable		 4e1vH-1sy7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 6 PRO A 125
GLY A 158
GLU A 156
GLN A 392
 None
 0.98A 4g0uA-1sy7A:
undetectable		 4g0uA-1sy7A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 5 PRO A 370
ASP A 369
ILE A 172
VAL A 169
 None
 1.43A 4hytA-1sy7A:
2.3		 4hytA-1sy7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 GLY A  97
ARG A 341
PHE A 355
ILE A 353
 None
None
HEM  A1883 ( 4.4A)
None
 0.89A 4j4vC-1sy7A:
undetectable		 4j4vC-1sy7A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.50A 4jksA-1sy7A:
3.8		 4jksA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.48A 4jksB-1sy7A:
3.8		 4jksB-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.49A 4jkuA-1sy7A:
4.2		 4jkuA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.49A 4k8kB-1sy7A:
3.8		 4k8kB-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.50A 4kalA-1sy7A:
3.8		 4kalA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.48A 4kalB-1sy7A:
3.8		 4kalB-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.50A 4lcaA-1sy7A:
3.8		 4lcaA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 9 VAL A 671
TYR A 683
GLY A 647
PHE A 646
GLY A 684
 None
 1.33A 4mm5A-1sy7A:
undetectable		 4mm5A-1sy7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 9 VAL A 671
TYR A 683
GLY A 647
PHE A 646
GLY A 684
 None
 1.40A 4mmeA-1sy7A:
undetectable		 4mmeA-1sy7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 9 VAL A 671
TYR A 683
GLY A 647
PHE A 646
GLY A 684
 None
 1.33A 4mmeB-1sy7A:
undetectable		 4mmeB-1sy7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 GLU A 307
ALA A 306
PHE A 252
 None
 0.64A 4v1fA-1sy7A:
undetectable		 4v1fA-1sy7A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 GLU A 307
ALA A 306
PHE A 252
 None
 0.62A 4v1fC-1sy7A:
undetectable		 4v1fC-1sy7A:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 11 PHE A 300
ALA A 114
VAL A 253
PHE A 255
GLY A 301
 None
 1.20A 4xp4A-1sy7A:
undetectable		 4xp4A-1sy7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 LYS A 650
ILE A 620
ILE A 561
 None
 0.70A 4y0qA-1sy7A:
3.5		 4y0qA-1sy7A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 MET A 233
HIS A  92
GLY A 164
ASN A 165
 None
HEM  A1883 ( 3.5A)
HDD  A1880 ( 3.9A)
HDD  A1880 ( 3.1A)
 1.34A 5a5zC-1sy7A:
undetectable		 5a5zC-1sy7A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ASP A 141
THR A 142
HIS A 648
LEU A 230
 None
 1.13A 5b1aA-1sy7A:
undetectable
5b1aC-1sy7A:
undetectable
5b1aP-1sy7A:
undetectable		 5b1aA-1sy7A:
20.82
5b1aC-1sy7A:
15.64
5b1aP-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 ASP A 141
THR A 142
HIS A 648
LEU A 230
 None
 1.13A 5b3sA-1sy7A:
undetectable
5b3sC-1sy7A:
0.0
5b3sP-1sy7A:
0.0		 5b3sA-1sy7A:
20.82
5b3sC-1sy7A:
15.64
5b3sP-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 TRP A 268
ASP A 141
THR A 142
HIS A 648
 None
 1.49A 5b3sN-1sy7A:
undetectable
5b3sP-1sy7A:
undetectable		 5b3sN-1sy7A:
20.82
5b3sP-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 TRP A 268
ASP A 141
THR A 142
HIS A 648
 None
 1.47A 5iy5A-1sy7A:
undetectable
5iy5C-1sy7A:
undetectable		 5iy5A-1sy7A:
20.82
5iy5C-1sy7A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 5 LEU A 490
PHE A 217
LEU A 506
TRP A 204
 None
 1.37A 5m10A-1sy7A:
3.4		 5m10A-1sy7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 TYR A 379
ASP A 369
VAL A 163
GLY A 164
 HDD  A1880 ( 4.0A)
None
HDD  A1880 ( 4.8A)
HDD  A1880 ( 3.9A)
 0.88A 5nzyA-1sy7A:
undetectable		 5nzyA-1sy7A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 CYH A 431
MET A 404
ASN A 405
 None
 1.30A 5qh8A-1sy7A:
0.0		 5qh8A-1sy7A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 TRP A 268
ASP A 141
THR A 142
HIS A 648
 None
 1.49A 5x1fN-1sy7A:
undetectable
5x1fP-1sy7A:
undetectable		 5x1fN-1sy7A:
20.82
5x1fP-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 5 VAL A 569
PRO A 623
GLY A 624
TYR A 566
 None
 1.32A 5x80A-1sy7A:
0.0
5x80B-1sy7A:
0.0		 5x80A-1sy7A:
11.80
5x80B-1sy7A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 5 PRO A 623
GLY A 624
TYR A 566
VAL A 569
 None
 1.31A 5x80C-1sy7A:
0.0
5x80D-1sy7A:
0.0		 5x80C-1sy7A:
11.80
5x80D-1sy7A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 LEU A 230
ASP A 141
THR A 142
HIS A 648
 None
 1.19A 5xdxC-1sy7A:
0.0
5xdxN-1sy7A:
0.0
5xdxP-1sy7A:
0.0		 5xdxC-1sy7A:
15.93
5xdxN-1sy7A:
20.82
5xdxP-1sy7A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 LEU A 230
ASP A 141
THR A 142
HIS A 648
 None
 1.16A 5z85C-1sy7A:
0.0
5z85N-1sy7A:
0.0
5z85P-1sy7A:
0.0		 5z85C-1sy7A:
15.64
5z85N-1sy7A:
20.82
5z85P-1sy7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 5 PHE A 696
VAL A 558
PRO A 623
VAL A 569
 None
 1.22A 6ekzA-1sy7A:
undetectable		 6ekzA-1sy7A:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 5 VAL A 193
PHE A 208
MET A 502
GLY A 500
 None
 1.35A 6hd4A-1sy7A:
undetectable		 6hd4A-1sy7A:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 10 LEU A 490
MET A 502
LEU A 513
MET A 216
THR A 218
 None
 1.41A 6hupD-1sy7A:
0.0
6hupE-1sy7A:
0.0		 6hupD-1sy7A:
8.96
6hupE-1sy7A:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		3 / 3 ASP A 278
LEU A 274
ARG A 147
 None
 0.82A 7dfrA-1sy7A:
undetectable		 7dfrA-1sy7A:
12.60