SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 LEU B 193
GLY B 194
ALA B 129
PRO B 130
 None
 0.51A 3huoA-1t04B:
undetectable		 3huoA-1t04B:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 SER B 134
VAL B 188
LEU B 142
PRO B 130
 None
 1.12A 3jq7C-1t04B:
undetectable		 3jq7C-1t04B:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 VAL B  72
GLU B  10
LYS B  23
PHE B  29
 None
 1.47A 3rv5C-1t04B:
undetectable
3rv5D-1t04B:
undetectable		 3rv5C-1t04B:
14.16
3rv5D-1t04B:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ALA B  92
THR B  91
VAL B 113
GLU B  89
 None
 0.75A 5ecmD-1t04B:
undetectable		 5ecmD-1t04B:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 7 ALA B  92
THR B  91
VAL B 113
GLU B  89
 None
 0.83A 5ecoD-1t04B:
undetectable		 5ecoD-1t04B:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 MET B  81
ASN B  77
VAL B  72
LEU B  70
 None
 1.19A 5xdhA-1t04B:
undetectable
5xdhC-1t04B:
undetectable		 5xdhA-1t04B:
16.57
5xdhC-1t04B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 MET B  81
ASN B  77
VAL B  72
LEU B  70
 None
 1.09A 5xdhB-1t04B:
undetectable		 5xdhB-1t04B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 MET B  81
ASN B  77
VAL B  72
LEU B  70
 None
 1.10A 5xdhA-1t04B:
undetectable
5xdhC-1t04B:
undetectable		 5xdhA-1t04B:
16.57
5xdhC-1t04B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 1t04 HUZAF ANTIBODY HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 MET B  81
ASN B  77
VAL B  72
LEU B  70
 None
 1.12A 5xdhD-1t04B:
undetectable		 5xdhD-1t04B:
16.57