SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 6 ASN A 176
GLY A 197
ILE A 198
ILE A 217
 None
 0.95A 1n49D-1t06A:
undetectable		 1n49D-1t06A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 12 THR A  18
GLY A  14
LEU A  56
VAL A   6
ILE A  71
 None
 0.94A 3frqB-1t06A:
undetectable		 3frqB-1t06A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 6 LEU A 123
SER A 126
ALA A 170
ARG A 166
 None
 0.94A 3ravA-1t06A:
undetectable		 3ravA-1t06A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 12 VAL A 190
ASN A 172
ILE A 160
VAL A 196
ILE A 198
 None
 1.21A 4eb6B-1t06A:
undetectable
4eb6C-1t06A:
undetectable		 4eb6B-1t06A:
18.81
4eb6C-1t06A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 5 GLU A 105
SER A 106
ARG A 234
PRO A  74
 None
 1.45A 4k17B-1t06A:
undetectable		 4k17B-1t06A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 10 ALA A  43
VAL A   6
GLU A   9
LEU A  10
LEU A  13
 None
 1.31A 4zmeB-1t06A:
undetectable		 4zmeB-1t06A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 5 LEU A 175
LYS A 157
LEU A 153
GLU A 154
 None
 1.27A 5weaA-1t06A:
undetectable		 5weaA-1t06A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 TYR A 182
GLY A 227
ILE A 180
LYS A 229
 None
 0.93A 6ag0A-1t06A:
undetectable		 6ag0A-1t06A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		4 / 8 TYR A 182
GLY A 227
ILE A 180
LYS A 229
 None
 0.89A 6ag0C-1t06A:
undetectable		 6ag0C-1t06A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 1t06 HYPOTHETICAL PROTEIN
(Bacillus
cereus) 		5 / 9 ALA A 170
SER A 169
ALA A 127
SER A 130
SER A  95
 None
 1.28A 6bklA-1t06A:
undetectable
6bklB-1t06A:
undetectable
6bklC-1t06A:
undetectable
6bklD-1t06A:
undetectable		 6bklA-1t06A:
8.81
6bklB-1t06A:
8.81
6bklC-1t06A:
8.81
6bklD-1t06A:
8.81