SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1t1v SH3 DOMAIN-BINDING
GLUTAMIC ACID-RICH
PROTEIN-LIKE 3
(Mus
musculus) 		3 / 3 ARG A  51
ASP A  39
ASN A  44
 None
 0.87A 2zzmA-1t1vA:
undetectable		 2zzmA-1t1vA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1t1v SH3 DOMAIN-BINDING
GLUTAMIC ACID-RICH
PROTEIN-LIKE 3
(Mus
musculus) 		3 / 3 VAL A   6
SER A   8
LEU A  37
 None
 0.72A 3n8xA-1t1vA:
undetectable		 3n8xA-1t1vA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 1t1v SH3 DOMAIN-BINDING
GLUTAMIC ACID-RICH
PROTEIN-LIKE 3
(Mus
musculus) 		4 / 6 SER A  19
TYR A  74
VAL A  78
THR A  25
 None
 1.05A 3tneA-1t1vA:
undetectable		 3tneA-1t1vA:
16.03